Abstract
Epigenetics is the study of heritable phenotype changes that do not involve alterations in the DNA sequence with the processes including DNA methylation, histone modifications and RNA-associated silencing [1,2]. Castellano-Castillo and colleagues have analysed the impact of metabolic syndrome on the global DNA methylation pattern and the DNA methylation of several genes in visceral adipose tissue [3]. They concluded that DNA methylation in adipose tissue of these patients is related to the aetiology of the syndrome. The role of DNA methylation in genes for adipogenesis, inflammation and lipid metabolism provides logical explanations for these changes in the development and progression of metabolic syndrome [3].
| Original language | English |
|---|---|
| Article number | 2699 |
| Number of pages | 4 |
| Journal | Journal of Clinical Medicine |
| Volume | 9 |
| Issue number | 9 |
| Publication status | Published - 2020 |
Open Access - Access Right Statement
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Keywords
- DNA
- adipose tissues
- epigenetics
- metabolic syndrome
- methylation
