TY - JOUR
T1 - Do the medial temporal lobes resolve perceptual interference?
AU - Harry, Bronson
AU - Postans, Mark
AU - Umla-Runge, Katja
PY - 2013
Y1 - 2013
N2 - The role of the medial temporal lobes (MTLs) in memory was first clearly established with the case of patient HM, who suffered from an inability to form new memories following surgical removal of bilateral MTLs (Scoville and Milner, 1957). Subsequent work in humans and animals revealed that memory impairment associated with MTL damage was related to a set of subcortical and cortical structures including the hippocampus, entorhinal, perirhinal, and parahippocampal cortex. Recent studies have shown that some of these subregions are domain sensitive with evidence indicating that the parahippocampal gyrus and hippocampus are involved in scene recognition, whereas the perirhinal cortex is involved in recognition of individual objects (Taylor et al., 2007; Staresina et al., 2011). Despite these considerable advances in our understanding of this brain region over the last 60 years, there remain unresolved questions regarding the fundamental role the MTL plays in perception and memory.
AB - The role of the medial temporal lobes (MTLs) in memory was first clearly established with the case of patient HM, who suffered from an inability to form new memories following surgical removal of bilateral MTLs (Scoville and Milner, 1957). Subsequent work in humans and animals revealed that memory impairment associated with MTL damage was related to a set of subcortical and cortical structures including the hippocampus, entorhinal, perirhinal, and parahippocampal cortex. Recent studies have shown that some of these subregions are domain sensitive with evidence indicating that the parahippocampal gyrus and hippocampus are involved in scene recognition, whereas the perirhinal cortex is involved in recognition of individual objects (Taylor et al., 2007; Staresina et al., 2011). Despite these considerable advances in our understanding of this brain region over the last 60 years, there remain unresolved questions regarding the fundamental role the MTL plays in perception and memory.
KW - impairment
KW - memory
KW - temporal lobes
UR - http://handle.uws.edu.au:8081/1959.7/uws:33839
U2 - 10.1523/JNEUROSCI.1767-13.2013
DO - 10.1523/JNEUROSCI.1767-13.2013
M3 - Article
SN - 0270-6474
VL - 33
SP - 10935
EP - 10937
JO - Journal of Neuroscience
JF - Journal of Neuroscience
IS - 27
ER -