Effect of aerobic exercise on leptin and PGC-1Î± gene expression in a unique cohort of morbidly obese Polynesians with type 2 diabetes

Irum Hayat; David Rowlands; Isabelle Lys; William Sukala; Birinder Cheema; Bernhard Breier; Murray Leikis; Jeremy Krebs; Rachel Page

Effect of aerobic exercise on leptin and PGC-1Î± gene expression in a unique cohort of morbidly obese Polynesians with type 2 diabetes

Irum Hayat
, David Rowlands
, Isabelle Lys
, William Sukala
, Birinder Cheema
, Bernhard Breier
, Murray Leikis
, Jeremy Krebs
, Rachel Page

Research output: Chapter in Book / Conference Paper › Conference Paper

Abstract

Incidence of type 2 diabetes (T2D) and obesity is rapidly escalating in New Zealand, particularly in Polynesians. Aerobic (AER) exercise can improve body composition, glycaemic control, and alter circulating metabolic hormones in individuals with T2D. PGC-1Î± is a key regulator in energy metabolism, controlling adaptive thermogenesis and glucose/fatty acid metabolism, and has been implicated in the pathogenesis of T2D. We have a unique cohort of morbidly obese Polynesian New Zealanders with T2D that have undergone intensive exercise training in the SPIRIT study. We are interested in examining the impact of exercise on energy metabolism in the skeletal muscle (SM) of this unique cohort.

Original language	English
Title of host publication	The Endocrine Society's 94th Annual Meeting and Expo, June 23–26, 2012, Houston, TX
Publisher	Endocrine Society
Number of pages	1
Publication status	Published - 2012
Event	Endocrine Society. Meeting - Duration: 1 Jan 2012 → …

Conference

Conference	Endocrine Society. Meeting
Period	1/01/12 → …

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

proteins
leptin
aerobic exercises
obesity
Polynesians
non-insulin-dependent diabetes

Cite this

@inproceedings{b8983dd1a3284f458406aca0da4424af,

title = "Effect of aerobic exercise on leptin and PGC-1{\^I}± gene expression in a unique cohort of morbidly obese Polynesians with type 2 diabetes",

abstract = "Incidence of type 2 diabetes (T2D) and obesity is rapidly escalating in New Zealand, particularly in Polynesians. Aerobic (AER) exercise can improve body composition, glycaemic control, and alter circulating metabolic hormones in individuals with T2D. PGC-1{\^I}± is a key regulator in energy metabolism, controlling adaptive thermogenesis and glucose/fatty acid metabolism, and has been implicated in the pathogenesis of T2D. We have a unique cohort of morbidly obese Polynesian New Zealanders with T2D that have undergone intensive exercise training in the SPIRIT study. We are interested in examining the impact of exercise on energy metabolism in the skeletal muscle (SM) of this unique cohort.",

keywords = "proteins, leptin, aerobic exercises, obesity, Polynesians, non-insulin-dependent diabetes",

author = "Irum Hayat and David Rowlands and Isabelle Lys and William Sukala and Birinder Cheema and Bernhard Breier and Murray Leikis and Jeremy Krebs and Rachel Page",

year = "2012",

language = "English",

booktitle = "The Endocrine Society's 94th Annual Meeting and Expo, June 23–26, 2012, Houston, TX",

publisher = "Endocrine Society",

note = "Endocrine Society. Meeting ; Conference date: 01-01-2012",

}

Hayat, I, Rowlands, D, Lys, I, Sukala, W, Cheema, B, Breier, B, Leikis, M, Krebs, J & Page, R 2012, Effect of aerobic exercise on leptin and PGC-1Î± gene expression in a unique cohort of morbidly obese Polynesians with type 2 diabetes. in The Endocrine Society's 94th Annual Meeting and Expo, June 23–26, 2012, Houston, TX. Endocrine Society, Endocrine Society. Meeting, 1/01/12.

Effect of aerobic exercise on leptin and PGC-1Î± gene expression in a unique cohort of morbidly obese Polynesians with type 2 diabetes. / Hayat, Irum; Rowlands, David; Lys, Isabelle et al.
The Endocrine Society's 94th Annual Meeting and Expo, June 23–26, 2012, Houston, TX. Endocrine Society, 2012.

Research output: Chapter in Book / Conference Paper › Conference Paper

TY - GEN

T1 - Effect of aerobic exercise on leptin and PGC-1Î± gene expression in a unique cohort of morbidly obese Polynesians with type 2 diabetes

AU - Hayat, Irum

AU - Rowlands, David

AU - Lys, Isabelle

AU - Sukala, William

AU - Cheema, Birinder

AU - Breier, Bernhard

AU - Leikis, Murray

AU - Krebs, Jeremy

AU - Page, Rachel

PY - 2012

Y1 - 2012

N2 - Incidence of type 2 diabetes (T2D) and obesity is rapidly escalating in New Zealand, particularly in Polynesians. Aerobic (AER) exercise can improve body composition, glycaemic control, and alter circulating metabolic hormones in individuals with T2D. PGC-1Î± is a key regulator in energy metabolism, controlling adaptive thermogenesis and glucose/fatty acid metabolism, and has been implicated in the pathogenesis of T2D. We have a unique cohort of morbidly obese Polynesian New Zealanders with T2D that have undergone intensive exercise training in the SPIRIT study. We are interested in examining the impact of exercise on energy metabolism in the skeletal muscle (SM) of this unique cohort.

AB - Incidence of type 2 diabetes (T2D) and obesity is rapidly escalating in New Zealand, particularly in Polynesians. Aerobic (AER) exercise can improve body composition, glycaemic control, and alter circulating metabolic hormones in individuals with T2D. PGC-1Î± is a key regulator in energy metabolism, controlling adaptive thermogenesis and glucose/fatty acid metabolism, and has been implicated in the pathogenesis of T2D. We have a unique cohort of morbidly obese Polynesian New Zealanders with T2D that have undergone intensive exercise training in the SPIRIT study. We are interested in examining the impact of exercise on energy metabolism in the skeletal muscle (SM) of this unique cohort.

KW - proteins

KW - leptin

KW - aerobic exercises

KW - obesity

KW - Polynesians

KW - non-insulin-dependent diabetes

UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:40524

M3 - Conference Paper

BT - The Endocrine Society's 94th Annual Meeting and Expo, June 23–26, 2012, Houston, TX

PB - Endocrine Society

T2 - Endocrine Society. Meeting

Y2 - 1 January 2012

ER -

Effect of aerobic exercise on leptin and PGC-1Î± gene expression in a unique cohort of morbidly obese Polynesians with type 2 diabetes

Abstract

Conference

UN SDGs

Keywords

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