Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis

Yan T. Wong; Spencer C. Chen; Yves A. Kerdraon; Penny J. Allen; M. F. McCombe; John W. Morley; Nigel H. Lovell; Gregg J. Suaning

Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis

Yan T. Wong
, Spencer C. Chen
, Yves A. Kerdraon
, Penny J. Allen
, M. F. McCombe
, John W. Morley
, Nigel H. Lovell
, Gregg J. Suaning

School of Medicine

Research output: Chapter in Book / Conference Paper › Conference Paper

Abstract

The key to successful, clinical application of therapeutic neurostimulators lies primarily with the safety and efficacy of their electrode-tissue interfaces. The authors posit that for electrical stimulation of the visual system, supra-choroidal electrode placement provides a safe, stable and readily-accessible site for implantation and the provision of electrical stimulation. The present paper explores the efficacy of supra-choroidal electrical stimulation of retinal neurons. Based upon recordings made with surface electrodes placed on the primary visual cortex, areas of activation in the cortex were shown to change when different areas on the supra-choroidal space were stimulated. Finally, the threshold to elicit a response from neurons in the visual cortex, was found to be 77.55 +/- 29.85 nC.

Original language	English
Title of host publication	Proceedings of the 30th Annual International Conference of the IEEE (EMBC08), 20th-24th August, Vancouver, Canada
Publisher	IEEE
Number of pages	4
ISBN (Print)	9781424418145
Publication status	Published - 2008
Event	Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Duration: 1 Jan 2008 → …

Conference

Conference	Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Period	1/01/08 → …

Keywords

electric stimulation therapy
biomedical engineering
retina
artificial organs
evoked potentials, visual
visual cortex

Cite this

@inproceedings{5a374d1b1a06458780098e8f05d9890a,

title = "Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis",

abstract = "The key to successful, clinical application of therapeutic neurostimulators lies primarily with the safety and efficacy of their electrode-tissue interfaces. The authors posit that for electrical stimulation of the visual system, supra-choroidal electrode placement provides a safe, stable and readily-accessible site for implantation and the provision of electrical stimulation. The present paper explores the efficacy of supra-choroidal electrical stimulation of retinal neurons. Based upon recordings made with surface electrodes placed on the primary visual cortex, areas of activation in the cortex were shown to change when different areas on the supra-choroidal space were stimulated. Finally, the threshold to elicit a response from neurons in the visual cortex, was found to be 77.55 +/- 29.85 nC.",

keywords = "electric stimulation therapy , biomedical engineering, retina, artificial organs, evoked potentials, visual , visual cortex",

author = "Wong, \{Yan T.\} and Chen, \{Spencer C.\} and Kerdraon, \{Yves A.\} and Allen, \{Penny J.\} and McCombe, \{M. F.\} and Morley, \{John W.\} and Lovell, \{Nigel H.\} and Suaning, \{Gregg J.\}",

year = "2008",

language = "English",

isbn = "9781424418145",

booktitle = "Proceedings of the 30th Annual International Conference of the IEEE (EMBC08), 20th-24th August, Vancouver, Canada",

publisher = "IEEE",

note = "Annual International Conference of the IEEE Engineering in Medicine and Biology Society ; Conference date: 01-01-2008",

}

Wong, YT, Chen, SC, Kerdraon, YA, Allen, PJ, McCombe, MF, Morley, JW, Lovell, NH & Suaning, GJ 2008, Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis. in Proceedings of the 30th Annual International Conference of the IEEE (EMBC08), 20th-24th August, Vancouver, Canada. IEEE, Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1/01/08.

TY - GEN

T1 - Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis

AU - Wong, Yan T.

AU - Chen, Spencer C.

AU - Kerdraon, Yves A.

AU - Allen, Penny J.

AU - McCombe, M. F.

AU - Morley, John W.

AU - Lovell, Nigel H.

AU - Suaning, Gregg J.

PY - 2008

Y1 - 2008

N2 - The key to successful, clinical application of therapeutic neurostimulators lies primarily with the safety and efficacy of their electrode-tissue interfaces. The authors posit that for electrical stimulation of the visual system, supra-choroidal electrode placement provides a safe, stable and readily-accessible site for implantation and the provision of electrical stimulation. The present paper explores the efficacy of supra-choroidal electrical stimulation of retinal neurons. Based upon recordings made with surface electrodes placed on the primary visual cortex, areas of activation in the cortex were shown to change when different areas on the supra-choroidal space were stimulated. Finally, the threshold to elicit a response from neurons in the visual cortex, was found to be 77.55 +/- 29.85 nC.

AB - The key to successful, clinical application of therapeutic neurostimulators lies primarily with the safety and efficacy of their electrode-tissue interfaces. The authors posit that for electrical stimulation of the visual system, supra-choroidal electrode placement provides a safe, stable and readily-accessible site for implantation and the provision of electrical stimulation. The present paper explores the efficacy of supra-choroidal electrical stimulation of retinal neurons. Based upon recordings made with surface electrodes placed on the primary visual cortex, areas of activation in the cortex were shown to change when different areas on the supra-choroidal space were stimulated. Finally, the threshold to elicit a response from neurons in the visual cortex, was found to be 77.55 +/- 29.85 nC.

KW - electric stimulation therapy

KW - biomedical engineering

KW - retina

KW - artificial organs

KW - evoked potentials, visual

KW - visual cortex

UR - http://handle.uws.edu.au:8081/1959.7/45277

M3 - Conference Paper

SN - 9781424418145

BT - Proceedings of the 30th Annual International Conference of the IEEE (EMBC08), 20th-24th August, Vancouver, Canada

PB - IEEE

T2 - Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Y2 - 1 January 2008

ER -

Efficacy of supra-choroidal, bipolar, electrical stimulation in a vision prosthesis

Abstract

Conference

Keywords

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