Empirical modeling of metabolic alkalosis induced by sodium bicarbonate ingestion

Simon Green, Jason C. Siegler

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Biphasic responses of blood HCO 3 - concentration and H+ concentration following ingestion of 3 doses of NaHCO 3 (0.1, 0.2, 0.3 g·kg -1) were assessed in 8 men. For HCO 3 - concentration, there were significant effects of dose on maximum responses and timing, as well amplitudes, onsets, and/or time constants of phases 1 and 2. Fewer significant effects of dose were observed for H+ concentration and additional data demonstrated differential effects of dose on HCO 3 - concentration and H+ concentration responses and underlying phases.
Original languageEnglish
Pages (from-to)1092-1095
Number of pages4
JournalApplied Physiology, Nutrition, and Metabolism
Volume41
Issue number10
Publication statusPublished - 2016

Bibliographical note

Publisher Copyright:
© 2016, Canadian Science Publishing. All rights reserved.

Keywords

  • alkalosis
  • magnitude
  • parameter estimation

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