Enhancing early dementia detection : a machine learning approach leveraging cognitive and neuroimaging features for optimal predictive performance

Muhammad Irfan, Seyed Shahrestani, Mahmoud Elkhodr

Research output: Contribution to journalArticlepeer-review

Abstract

Dementia, including Alzheimer’s Disease (AD), is a complex condition, and early detection remains a formidable challenge due to limited patient records and uncertainty in identifying relevant features. This paper proposes a machine learning approach to address this issue, utilizing cognitive and neuroimaging features for training predictive models. This study highlighted the viability of cognitive test scores in dementia detection—a procedure that offers the advantage of simplicity. The AdaBoost Ensemble model, trained on cognitive features, displayed a robust performance with an accuracy rate of approximately 83%. Notably, this model surpassed benchmark models such as the Artificial Neural Network, Support Vector Machine, and Naïve Bayes. This study underscores the potential of cognitive tests and machine learning for early dementia detection.

Original languageEnglish
Article number10470
Number of pages19
JournalApplied Sciences
Volume13
Issue number18
DOIs
Publication statusPublished - Sept 2023

Bibliographical note

Publisher Copyright:
© 2023 by the authors.

Open Access - Access Right Statement

© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

Keywords

  • alzheimer
  • neighborhood component analysis (NCA)
  • cognitive features
  • dementia
  • neuroimaging features
  • machine learning

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