TY - JOUR
T1 - Enhancing the separation performance of the first-generation silica monolith using active flow technology : parallel segmented flow mode of operation
AU - Soliven, Arianne
AU - Foley, Dominic
AU - Pereira, Luisa
AU - Dennis, Gary R.
AU - Shalliker, R. Andrew
AU - Cabrera, Karin
AU - Ritchie, Harald
AU - Edge, Tony
PY - 2014
Y1 - 2014
N2 - Active flow technology (AFT) columns are designed to minimise inefficient flow processes associated with the column wall and radial heterogeneity of the stationary phase bed. This study is the first to investigate AFT on an analytical scale 4.6. mm internal diameter first-generation silica monolith. The performance was compared to a conventional first-generation silica monolith and it was observed that the AFT monolith had an increase in efficiency values that ranged from 15 to 111%; the trend demonstrating efficiency gains increasing as the volumetric flow to the detector was decreased, but with no loss in sensitivity.
AB - Active flow technology (AFT) columns are designed to minimise inefficient flow processes associated with the column wall and radial heterogeneity of the stationary phase bed. This study is the first to investigate AFT on an analytical scale 4.6. mm internal diameter first-generation silica monolith. The performance was compared to a conventional first-generation silica monolith and it was observed that the AFT monolith had an increase in efficiency values that ranged from 15 to 111%; the trend demonstrating efficiency gains increasing as the volumetric flow to the detector was decreased, but with no loss in sensitivity.
UR - http://handle.uws.edu.au:8081/1959.7/546191
U2 - 10.1016/j.chroma.2014.01.031
DO - 10.1016/j.chroma.2014.01.031
M3 - Article
C2 - 24565232
SN - 0021-9673
VL - 1334
SP - 16
EP - 19
JO - Journal of Chromatography A
JF - Journal of Chromatography A
ER -