TY - JOUR
T1 - Estimated human absorbed dose of 177Lu-BPAMD based on mice data: Comparison with 177Lu-EDTMP
AU - Yousefnia, Hassan
AU - Zolghadri, Samaneh
AU - Shanehsazzadeh, Saeed
PY - 2015/10
Y1 - 2015/10
N2 - In this work, the absorbed dose of human organs for Lu-177-BPAMD was evaluated based on biodistribution studies into the Syrian mice by RADAR method and was compared with Lu-177-EDTMP as the only clinically used Lu-177 bone-seeking agent. The highest absorbed dose for both Lu-177-BPAMD and Lu-177-EDTMP is observed on the bone surface with 8.007 and 4.802 mSv/MBq. Generally, Lu-177-BPAMD has considerable characteristics compared with Lu-177-EDTMP and can be considered as a promising agent for the bone pain palliation therapy.
AB - In this work, the absorbed dose of human organs for Lu-177-BPAMD was evaluated based on biodistribution studies into the Syrian mice by RADAR method and was compared with Lu-177-EDTMP as the only clinically used Lu-177 bone-seeking agent. The highest absorbed dose for both Lu-177-BPAMD and Lu-177-EDTMP is observed on the bone surface with 8.007 and 4.802 mSv/MBq. Generally, Lu-177-BPAMD has considerable characteristics compared with Lu-177-EDTMP and can be considered as a promising agent for the bone pain palliation therapy.
UR - https://go.openathens.net/redirector/westernsydney.edu.au?url=https://doi.org/ 10.1016/j.apradiso.2015.06.033
U2 - 10.1016/j.apradiso.2015.06.033
DO - 10.1016/j.apradiso.2015.06.033
M3 - Article
SN - 0969-8043
VL - 104
SP - 128
EP - 135
JO - Applied Radiation and Isotopes
JF - Applied Radiation and Isotopes
ER -
