Evaluation of hypoglycemic and antihyperglycemic effects of Datura metel (Linn.) seeds in normal and alloxan-induced diabetic rats

B. Krishna Murthy; S. Nammi; M. K. Kota; R. V. Krishna Rao; N. Koteswara Rao; A. Annapurna

doi:10.1016/j.jep.2003.12.010

Evaluation of hypoglycemic and antihyperglycemic effects of Datura metel (Linn.) seeds in normal and alloxan-induced diabetic rats

B. Krishna Murthy
, S. Nammi
, M. K. Kota
, R. V. Krishna Rao
, N. Koteswara Rao
, A. Annapurna

Andhra University

Research output: Contribution to journal › Article › peer-review

69 Citations (Scopus)

Abstract

The seed powder of Datura metel was tested for its hypoglycemic activity in normal and alloxan-induced diabetic rats. Graded doses (25, 50 and 75mg/kg, p.o.) of the seed powder when given to both normal and diabetic rats produced significant reduction in blood glucose at the 8h. The effect was found to be dose dependent with all treatments at the doses administered.

Original language	English
Pages (from-to)	95-98
Number of pages	4
Journal	Journal of Ethnopharmacology
Volume	91
Issue number	1
DOIs	https://doi.org/10.1016/j.jep.2003.12.010
Publication status	Published - Mar 2004
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Alloxan
Blood glucose
Datura metel
Diabetes mellitus
Rats

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10.1016/j.jep.2003.12.010

Cite this

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abstract = "The seed powder of Datura metel was tested for its hypoglycemic activity in normal and alloxan-induced diabetic rats. Graded doses (25, 50 and 75mg/kg, p.o.) of the seed powder when given to both normal and diabetic rats produced significant reduction in blood glucose at the 8h. The effect was found to be dose dependent with all treatments at the doses administered.",

keywords = "Alloxan, Blood glucose, Datura metel, Diabetes mellitus, Rats",

author = "\{Krishna Murthy\}, B. and S. Nammi and Kota, \{M. K.\} and \{Krishna Rao\}, \{R. V.\} and \{Koteswara Rao\}, N. and A. Annapurna",

year = "2004",

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doi = "10.1016/j.jep.2003.12.010",

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AU - Krishna Murthy, B.

AU - Nammi, S.

AU - Kota, M. K.

AU - Krishna Rao, R. V.

AU - Koteswara Rao, N.

AU - Annapurna, A.

PY - 2004/3

Y1 - 2004/3

N2 - The seed powder of Datura metel was tested for its hypoglycemic activity in normal and alloxan-induced diabetic rats. Graded doses (25, 50 and 75mg/kg, p.o.) of the seed powder when given to both normal and diabetic rats produced significant reduction in blood glucose at the 8h. The effect was found to be dose dependent with all treatments at the doses administered.

AB - The seed powder of Datura metel was tested for its hypoglycemic activity in normal and alloxan-induced diabetic rats. Graded doses (25, 50 and 75mg/kg, p.o.) of the seed powder when given to both normal and diabetic rats produced significant reduction in blood glucose at the 8h. The effect was found to be dose dependent with all treatments at the doses administered.

KW - Alloxan

KW - Blood glucose

KW - Datura metel

KW - Diabetes mellitus

KW - Rats

UR - https://www.scopus.com/pages/publications/1442351150

U2 - 10.1016/j.jep.2003.12.010

DO - 10.1016/j.jep.2003.12.010

M3 - Article

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JF - Journal of Ethnopharmacology

IS - 1

ER -

Evaluation of hypoglycemic and antihyperglycemic effects of Datura metel (Linn.) seeds in normal and alloxan-induced diabetic rats

Abstract

UN SDGs

Keywords

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