Exercise training effects on mitochondrial activity and oxidative capacity in skeletal muscle tissue of Polynesian individuals with type 2 diabetes and grade 3 obesity

I. Hayat, R. Bramley, A. Hollings, I. Lys, W. Sukala, B. Cheema, D. Rowlands, B. Breier, J. Krebs, R. Page

Research output: Chapter in Book / Conference PaperConference Paper

Abstract

![CDATA[The South Pacific Island Resist diabetes with Intense Training (SPIRIT) study is the first randomised trial of clinical exercise training in a cohort of Polynesian New Zealanders with type 2 diabetes mellitus (T2DM) and grade 3 obesity (n=18; BMI 43.8 ± 9.5 kg/m2; mean waist circumference 128.7 ± 18.7 cm). Several studies have demonstrated that mitochondrial activity and lipid metabolism in skeletal muscle of people with T2DM decreases and the oxidative capacity of the tissue declines. We propose that the metabolic adaptation in the SPIRIT study cohort is either delayed or overwhelmed by the effect of increased fat mass.]]
Original languageEnglish
Title of host publicationAustralian Diabetes Society & Australian Diabetes Educators Association (ADS-ADEA) Annual Scientific Meeting, Perth Convention and Exhibition Centre, WA, 31st August – 2 September 2011 : Meeting Proceedings and Abstract Book 2011
PublisherAustralian Diabetes Society
Pages123-
Number of pages1
Publication statusPublished - 2011
EventAustralian Diabetes Society & Australian Diabetes Educators Association. Scientific Meeting -
Duration: 1 Jan 2011 → …

Conference

ConferenceAustralian Diabetes Society & Australian Diabetes Educators Association. Scientific Meeting
Period1/01/11 → …

Keywords

  • exercise
  • Polynesians
  • non-insulin-dependent diabetes
  • obesity

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