Exercise training effects on mitochondrial activity and oxidative capacity in skeletal muscle tissue of Polynesian individuals with type 2 diabetes and grade 3 obesity

I. Hayat; R. Bramley; A. Hollings; I. Lys; W. Sukala; B. Cheema; D. Rowlands; B. Breier; J. Krebs; R. Page

Exercise training effects on mitochondrial activity and oxidative capacity in skeletal muscle tissue of Polynesian individuals with type 2 diabetes and grade 3 obesity

I. Hayat
, R. Bramley
, A. Hollings
, I. Lys
, W. Sukala
, B. Cheema
, D. Rowlands
, B. Breier
, J. Krebs
, R. Page

Research output: Chapter in Book / Conference Paper › Conference Paper

Abstract

The South Pacific Island Resist diabetes with Intense Training (SPIRIT) study is the first randomised trial of clinical exercise training in a cohort of Polynesian New Zealanders with type 2 diabetes mellitus (T2DM) and grade 3 obesity (n=18; BMI 43.8 Â± 9.5 kg/m2; mean waist circumference 128.7 Â± 18.7 cm). Several studies have demonstrated that mitochondrial activity and lipid metabolism in skeletal muscle of people with T2DM decreases and the oxidative capacity of the tissue declines. We propose that the metabolic adaptation in the SPIRIT study cohort is either delayed or overwhelmed by the effect of increased fat mass.

Original language	English
Title of host publication	Australian Diabetes Society & Australian Diabetes Educators Association (ADS-ADEA) Annual Scientific Meeting, Perth Convention and Exhibition Centre, WA, 31st August – 2 September 2011 : Meeting Proceedings and Abstract Book 2011
Publisher	Australian Diabetes Society
Pages	123-
Number of pages	1
Publication status	Published - 2011
Event	Australian Diabetes Society & Australian Diabetes Educators Association. Scientific Meeting - Duration: 1 Jan 2011 → …

Conference

Conference	Australian Diabetes Society & Australian Diabetes Educators Association. Scientific Meeting
Period	1/01/11 → …

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

exercise
Polynesians
non-insulin-dependent diabetes
obesity

Cite this

Hayat, I., Bramley, R., Hollings, A., Lys, I., Sukala, W., Cheema, B., Rowlands, D., Breier, B., Krebs, J., & Page, R. (2011). Exercise training effects on mitochondrial activity and oxidative capacity in skeletal muscle tissue of Polynesian individuals with type 2 diabetes and grade 3 obesity. In Australian Diabetes Society & Australian Diabetes Educators Association (ADS-ADEA) Annual Scientific Meeting, Perth Convention and Exhibition Centre, WA, 31st August – 2 September 2011 : Meeting Proceedings and Abstract Book 2011 (pp. 123-). Australian Diabetes Society.

Hayat, I. ; Bramley, R. ; Hollings, A. et al. / Exercise training effects on mitochondrial activity and oxidative capacity in skeletal muscle tissue of Polynesian individuals with type 2 diabetes and grade 3 obesity. Australian Diabetes Society & Australian Diabetes Educators Association (ADS-ADEA) Annual Scientific Meeting, Perth Convention and Exhibition Centre, WA, 31st August – 2 September 2011 : Meeting Proceedings and Abstract Book 2011. Australian Diabetes Society, 2011. pp. 123-

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title = "Exercise training effects on mitochondrial activity and oxidative capacity in skeletal muscle tissue of Polynesian individuals with type 2 diabetes and grade 3 obesity",

abstract = "The South Pacific Island Resist diabetes with Intense Training (SPIRIT) study is the first randomised trial of clinical exercise training in a cohort of Polynesian New Zealanders with type 2 diabetes mellitus (T2DM) and grade 3 obesity (n=18; BMI 43.8 {\^A}± 9.5 kg/m2; mean waist circumference 128.7 {\^A}± 18.7 cm). Several studies have demonstrated that mitochondrial activity and lipid metabolism in skeletal muscle of people with T2DM decreases and the oxidative capacity of the tissue declines. We propose that the metabolic adaptation in the SPIRIT study cohort is either delayed or overwhelmed by the effect of increased fat mass.",

keywords = "exercise, Polynesians, non-insulin-dependent diabetes, obesity",

author = "I. Hayat and R. Bramley and A. Hollings and I. Lys and W. Sukala and B. Cheema and D. Rowlands and B. Breier and J. Krebs and R. Page",

year = "2011",

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note = "Australian Diabetes Society \& Australian Diabetes Educators Association. Scientific Meeting ; Conference date: 01-01-2011",

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Hayat, I, Bramley, R, Hollings, A, Lys, I, Sukala, W, Cheema, B, Rowlands, D, Breier, B, Krebs, J & Page, R 2011, Exercise training effects on mitochondrial activity and oxidative capacity in skeletal muscle tissue of Polynesian individuals with type 2 diabetes and grade 3 obesity. in Australian Diabetes Society & Australian Diabetes Educators Association (ADS-ADEA) Annual Scientific Meeting, Perth Convention and Exhibition Centre, WA, 31st August – 2 September 2011 : Meeting Proceedings and Abstract Book 2011. Australian Diabetes Society, pp. 123-, Australian Diabetes Society & Australian Diabetes Educators Association. Scientific Meeting, 1/01/11.

Exercise training effects on mitochondrial activity and oxidative capacity in skeletal muscle tissue of Polynesian individuals with type 2 diabetes and grade 3 obesity. / Hayat, I.; Bramley, R.; Hollings, A. et al.
Australian Diabetes Society & Australian Diabetes Educators Association (ADS-ADEA) Annual Scientific Meeting, Perth Convention and Exhibition Centre, WA, 31st August – 2 September 2011 : Meeting Proceedings and Abstract Book 2011. Australian Diabetes Society, 2011. p. 123-.

Research output: Chapter in Book / Conference Paper › Conference Paper

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T1 - Exercise training effects on mitochondrial activity and oxidative capacity in skeletal muscle tissue of Polynesian individuals with type 2 diabetes and grade 3 obesity

AU - Hayat, I.

AU - Bramley, R.

AU - Hollings, A.

AU - Lys, I.

AU - Sukala, W.

AU - Cheema, B.

AU - Rowlands, D.

AU - Breier, B.

AU - Krebs, J.

AU - Page, R.

PY - 2011

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N2 - The South Pacific Island Resist diabetes with Intense Training (SPIRIT) study is the first randomised trial of clinical exercise training in a cohort of Polynesian New Zealanders with type 2 diabetes mellitus (T2DM) and grade 3 obesity (n=18; BMI 43.8 Â± 9.5 kg/m2; mean waist circumference 128.7 Â± 18.7 cm). Several studies have demonstrated that mitochondrial activity and lipid metabolism in skeletal muscle of people with T2DM decreases and the oxidative capacity of the tissue declines. We propose that the metabolic adaptation in the SPIRIT study cohort is either delayed or overwhelmed by the effect of increased fat mass.

AB - The South Pacific Island Resist diabetes with Intense Training (SPIRIT) study is the first randomised trial of clinical exercise training in a cohort of Polynesian New Zealanders with type 2 diabetes mellitus (T2DM) and grade 3 obesity (n=18; BMI 43.8 Â± 9.5 kg/m2; mean waist circumference 128.7 Â± 18.7 cm). Several studies have demonstrated that mitochondrial activity and lipid metabolism in skeletal muscle of people with T2DM decreases and the oxidative capacity of the tissue declines. We propose that the metabolic adaptation in the SPIRIT study cohort is either delayed or overwhelmed by the effect of increased fat mass.

KW - exercise

KW - Polynesians

KW - non-insulin-dependent diabetes

KW - obesity

UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:40428

M3 - Conference Paper

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BT - Australian Diabetes Society & Australian Diabetes Educators Association (ADS-ADEA) Annual Scientific Meeting, Perth Convention and Exhibition Centre, WA, 31st August – 2 September 2011 : Meeting Proceedings and Abstract Book 2011

PB - Australian Diabetes Society

T2 - Australian Diabetes Society & Australian Diabetes Educators Association. Scientific Meeting

Y2 - 1 January 2011

ER -

Hayat I, Bramley R, Hollings A, Lys I, Sukala W, Cheema B et al. Exercise training effects on mitochondrial activity and oxidative capacity in skeletal muscle tissue of Polynesian individuals with type 2 diabetes and grade 3 obesity. In Australian Diabetes Society & Australian Diabetes Educators Association (ADS-ADEA) Annual Scientific Meeting, Perth Convention and Exhibition Centre, WA, 31st August – 2 September 2011 : Meeting Proceedings and Abstract Book 2011. Australian Diabetes Society. 2011. p. 123-

Exercise training effects on mitochondrial activity and oxidative capacity in skeletal muscle tissue of Polynesian individuals with type 2 diabetes and grade 3 obesity

Abstract

Conference

UN SDGs

Keywords

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