TY - JOUR
T1 - Experiments to detect long-range heteronuclear shift correlations
T2 - LR-J-HSMQC
AU - Torres, A. M.
AU - Bubb, W. A.
AU - Kuchel, P. W.
PY - 2002
Y1 - 2002
N2 - The utility of the J-HSMQC experiment to detect long-range CH correlations was investigated. Two new long-range J-compensated pulse sequences, LR-J-HSMQC(80,27) and LR-J-HSMQC(27,80), were developed using the (3βx)βy composite 90° pulse sequence. These two experiments were shown to be effective for long-range coupling constants, nJCH, that were greater than 3 Hz. Although the overall sensitivities of the long-range J-HSMQC experiments were slightly lower than that of the conventional decoupled HMBC experiment, their 2D maps showed additional cross peaks that could be useful in structure elucidation. LR-J-HSMQC(27,80) was very efficient in yielding two- and four-bond relay correlations. The utility of the new sequences is demonstrated with strychnine as the sample.
AB - The utility of the J-HSMQC experiment to detect long-range CH correlations was investigated. Two new long-range J-compensated pulse sequences, LR-J-HSMQC(80,27) and LR-J-HSMQC(27,80), were developed using the (3βx)βy composite 90° pulse sequence. These two experiments were shown to be effective for long-range coupling constants, nJCH, that were greater than 3 Hz. Although the overall sensitivities of the long-range J-HSMQC experiments were slightly lower than that of the conventional decoupled HMBC experiment, their 2D maps showed additional cross peaks that could be useful in structure elucidation. LR-J-HSMQC(27,80) was very efficient in yielding two- and four-bond relay correlations. The utility of the new sequences is demonstrated with strychnine as the sample.
UR - http://www.scopus.com/inward/record.url?scp=0036040745&partnerID=8YFLogxK
U2 - 10.1006/jmre.2002.2563
DO - 10.1006/jmre.2002.2563
M3 - Article
C2 - 12165260
AN - SCOPUS:0036040745
SN - 1090-7807
VL - 156
SP - 249
EP - 257
JO - Journal of Magnetic Resonance
JF - Journal of Magnetic Resonance
IS - 2
ER -