Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma

S. Y. Kwun; Christopher J. Scarlett; James G. Kench; E. Y. M. Sum; Davendra Segara; Emily K. Colvin; Johana M. Susanto; Peter H. Cosman; Cheok Soon Lee; Elizabeth A. Musgrove; Geoffrey J. Lindeman; Susan M. Henshall; Jane E. Visvader; Andrew V. Biankin

Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma

S. Y. Kwun, Christopher J. Scarlett, James G. Kench, E. Y. M. Sum, Davendra Segara, Emily K. Colvin, Johana M. Susanto, Peter H. Cosman, Cheok Soon Lee, Elizabeth A. Musgrove, Geoffrey J. Lindeman, Susan M. Henshall, Jane E. Visvader, Andrew V. Biankin

School of Medicine

Research output: Contribution to journal › Article

23 Citations (Scopus)

Abstract

Identification of a biomarker of prognosis and response to therapy that can be assessed preoperatively would significantly improve overall outcomes for patients with pancreatic cancer. In this study, patients whose tumours exhibited high LMO4 expression had a significant survival advantage following operative resection, whereas the survival of those patients whose tumours had low or no LMO4 expression was not significantly different when resection was compared with operative biopsy alone.

Original language	English
Pages (from-to)	537-541
Number of pages	5
Journal	British Journal of Cancer
Volume	98
Issue number	3
Publication status	Published - 12 Feb 2008

Keywords

LMO4
cancer
pancreas
prognosis
surgical resection
therapeutic response

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma",

abstract = "Identification of a biomarker of prognosis and response to therapy that can be assessed preoperatively would significantly improve overall outcomes for patients with pancreatic cancer. In this study, patients whose tumours exhibited high LMO4 expression had a significant survival advantage following operative resection, whereas the survival of those patients whose tumours had low or no LMO4 expression was not significantly different when resection was compared with operative biopsy alone.",

keywords = "LMO4, cancer, pancreas, prognosis, surgical resection, therapeutic response",

author = "Kwun, {S. Y.} and Scarlett, {Christopher J.} and Kench, {James G.} and Sum, {E. Y. M.} and Davendra Segara and Colvin, {Emily K.} and Susanto, {Johana M.} and Cosman, {Peter H.} and Lee, {Cheok Soon} and Musgrove, {Elizabeth A.} and Lindeman, {Geoffrey J.} and Henshall, {Susan M.} and Visvader, {Jane E.} and Biankin, {Andrew V.}",

year = "2008",

month = feb,

day = "12",

language = "English",

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pages = "537--541",

journal = "British Journal of Cancer",

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T1 - Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma

AU - Kwun, S. Y.

AU - Scarlett, Christopher J.

AU - Kench, James G.

AU - Sum, E. Y. M.

AU - Segara, Davendra

AU - Colvin, Emily K.

AU - Susanto, Johana M.

AU - Cosman, Peter H.

AU - Lee, Cheok Soon

AU - Musgrove, Elizabeth A.

AU - Lindeman, Geoffrey J.

AU - Henshall, Susan M.

AU - Visvader, Jane E.

AU - Biankin, Andrew V.

PY - 2008/2/12

Y1 - 2008/2/12

N2 - Identification of a biomarker of prognosis and response to therapy that can be assessed preoperatively would significantly improve overall outcomes for patients with pancreatic cancer. In this study, patients whose tumours exhibited high LMO4 expression had a significant survival advantage following operative resection, whereas the survival of those patients whose tumours had low or no LMO4 expression was not significantly different when resection was compared with operative biopsy alone.

AB - Identification of a biomarker of prognosis and response to therapy that can be assessed preoperatively would significantly improve overall outcomes for patients with pancreatic cancer. In this study, patients whose tumours exhibited high LMO4 expression had a significant survival advantage following operative resection, whereas the survival of those patients whose tumours had low or no LMO4 expression was not significantly different when resection was compared with operative biopsy alone.

KW - LMO4

KW - cancer

KW - pancreas

KW - prognosis

KW - surgical resection

KW - therapeutic response

UR - http://handle.uws.edu.au:8081/1959.7/488076

M3 - Article

C2 - 18231110

SN - 0007-0920

VL - 98

SP - 537

EP - 541

JO - British Journal of Cancer

JF - British Journal of Cancer

IS - 3

ER -

Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma

Abstract

Keywords

UN SDGs

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