TY - JOUR
T1 - Extra-mammary Paget's disease rising from a non-invasive rectal adenoma
AU - Harb, M.
AU - Prince, D. S.
AU - Bassan, M.
AU - Mackenzie, S.
AU - Connor, S. J.
AU - Rutland, T.
PY - 2022
Y1 - 2022
N2 - Extra-mammary Paget’s disease (EMPD) is a chronic erythematous dermatological condition which can be classified as either primary or secondary. Primary EMPD is thought to arise from skin adnexal apocrine glands, whereas, secondary tends to arise from visceral carcinomas, such as a colorectal or gynaecological source. EMPD developing from a non-invasive colorectal adenoma is incredibly rare, with very few documented cases in the current literature. As such, there is very little guidance on treatment and prognosis, although reports suggest these patients may have better outcomes. Thus, it is critical for a clinical pathological consensus to avoid over treatment. This case report presents an incidental finding of EMPD in a patient with a rectal tubulo-villous adenoma (TVA).
AB - Extra-mammary Paget’s disease (EMPD) is a chronic erythematous dermatological condition which can be classified as either primary or secondary. Primary EMPD is thought to arise from skin adnexal apocrine glands, whereas, secondary tends to arise from visceral carcinomas, such as a colorectal or gynaecological source. EMPD developing from a non-invasive colorectal adenoma is incredibly rare, with very few documented cases in the current literature. As such, there is very little guidance on treatment and prognosis, although reports suggest these patients may have better outcomes. Thus, it is critical for a clinical pathological consensus to avoid over treatment. This case report presents an incidental finding of EMPD in a patient with a rectal tubulo-villous adenoma (TVA).
UR - https://hdl.handle.net/1959.7/uws:68387
U2 - 10.1016/j.pathol.2021.11.011
DO - 10.1016/j.pathol.2021.11.011
M3 - Article
SN - 0031-3025
VL - 54
SP - 826
EP - 828
JO - Pathology
JF - Pathology
IS - 6
ER -