Free radicals, lipids and protein degradation

Simon P. Wolff; Anthony Garner; Roger T. Dean

doi:10.1016/0968-0004(86)90228-8

Free radicals, lipids and protein degradation

Simon P. Wolff, Anthony Garner, Roger T. Dean

Brunel University London

Research output: Contribution to journal › Article › peer-review

493 Citations (Scopus)

Abstract

Primary oxygen radicals produced in cells and their secondary lipid radical intermediates can modify and fragment proteins. The products are often more susceptible to enzymatic hydrolysis and so radical fluxes may accelerate proteolysis inside and outside cells.

Original language	English
Pages (from-to)	27-31
Number of pages	5
Journal	Trends in Biochemical Sciences
Volume	11
Issue number	1
DOIs	https://doi.org/10.1016/0968-0004(86)90228-8
Publication status	Published - Jan 1986
Externally published	Yes

Access to Document

10.1016/0968-0004(86)90228-8

Cite this

@article{6a1f550ddc1a41afb8a2e0b2abcedae7,

title = "Free radicals, lipids and protein degradation",

abstract = "Primary oxygen radicals produced in cells and their secondary lipid radical intermediates can modify and fragment proteins. The products are often more susceptible to enzymatic hydrolysis and so radical fluxes may accelerate proteolysis inside and outside cells.",

author = "Wolff, {Simon P.} and Anthony Garner and Dean, {Roger T.}",

year = "1986",

month = jan,

doi = "10.1016/0968-0004(86)90228-8",

language = "English",

volume = "11",

pages = "27--31",

journal = "Trends in Biochemical Sciences",

issn = "0968-0004",

publisher = "Elsevier Ltd.",

number = "1",

}

TY - JOUR

T1 - Free radicals, lipids and protein degradation

AU - Wolff, Simon P.

AU - Garner, Anthony

AU - Dean, Roger T.

PY - 1986/1

Y1 - 1986/1

N2 - Primary oxygen radicals produced in cells and their secondary lipid radical intermediates can modify and fragment proteins. The products are often more susceptible to enzymatic hydrolysis and so radical fluxes may accelerate proteolysis inside and outside cells.

AB - Primary oxygen radicals produced in cells and their secondary lipid radical intermediates can modify and fragment proteins. The products are often more susceptible to enzymatic hydrolysis and so radical fluxes may accelerate proteolysis inside and outside cells.

UR - http://www.scopus.com/inward/record.url?scp=0022644072&partnerID=8YFLogxK

U2 - 10.1016/0968-0004(86)90228-8

DO - 10.1016/0968-0004(86)90228-8

M3 - Article

AN - SCOPUS:0022644072

SN - 0968-0004

VL - 11

SP - 27

EP - 31

JO - Trends in Biochemical Sciences

JF - Trends in Biochemical Sciences

IS - 1

ER -

Free radicals, lipids and protein degradation

Abstract

Access to Document

Other files and links

Fingerprint

Cite this