TY - JOUR
T1 - Fulminant methicillin-sensitive Staphylococcus aureus infection in a healthy adolescent, highlighting 'Panton-Valentine leucocidin syndrome'
AU - Swaminathan, A.
AU - Massasso, D.
AU - Gotis-Graham, I.
AU - Gosbell, I.
PY - 2006
Y1 - 2006
N2 - A 14-year-old immunocompetent adolescent presented systemically unwell with left knee septic arthritis. Within several days, disseminated bone and soft tissue collections became evident, associated with deep venous thrombosis and pulmonary involvement. Methicillin-sensitive Staphylococcus aureus was isolated, harbouring Panton-Valentine leucocidin genes. Aggressive antibiotic and surgical therapies eventually lead to recovery. Intrafamilial spread of the pathogenic isolate was shown by household screening. This presentation is consistent with 'PVL Syndrome' and is typical of severe S. aureus infection emerging in young populations globally.
AB - A 14-year-old immunocompetent adolescent presented systemically unwell with left knee septic arthritis. Within several days, disseminated bone and soft tissue collections became evident, associated with deep venous thrombosis and pulmonary involvement. Methicillin-sensitive Staphylococcus aureus was isolated, harbouring Panton-Valentine leucocidin genes. Aggressive antibiotic and surgical therapies eventually lead to recovery. Intrafamilial spread of the pathogenic isolate was shown by household screening. This presentation is consistent with 'PVL Syndrome' and is typical of severe S. aureus infection emerging in young populations globally.
KW - Staphylococcus aureus
KW - deep vein thrombosis
UR - http://handle.uws.edu.au:8081/1959.7/505280
U2 - 10.1111/j.1445-5994.2006.01220.x
DO - 10.1111/j.1445-5994.2006.01220.x
M3 - Article
SN - 1444-0903
VL - 36
SP - 744
EP - 747
JO - Internal Medicine Journal
JF - Internal Medicine Journal
IS - 11
ER -
