Furosemide for transient tachypnoea of the newborn : intervention review

Manal Kassab, Wadah M. Khriesat, Hiba Bawadi, Jasim Anabrees

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    32 Citations (Scopus)

    Abstract

    It is common for full term infants born by elective caesarean section to have laboured, rapid breathing (tachypnoea) and to require oxygen for about 48 hours. This transient tachypnoea of the newborn (TTN) is responsible for about half of all cases of neonatal respiratory distress. Although it is transient and not usually serious, the condition requires admission to a neonatal intensive care unit, involves separation of mother and baby, and uses of expensive resources. Furosemide is a diuretic medication which, in other circumstances, may reduce fluid in the lungs. In our updated review, we included two randomised controlled trials involving 100 babies that compared the effect of furosemide given orally or intravenously versus placebo or no treatment in babies of less than seven days of age, born at 37 or more weeks of gestation with TTN. We found no significant benefit from using furosemide in babies with TTN.
    Original languageEnglish
    Article numberArt. No.: CD003064
    Pages (from-to)1-16
    Number of pages17
    JournalCochrane Database of Systematic Reviews
    Volume6
    DOIs
    Publication statusPublished - 2013

    Open Access - Access Right Statement

    This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2013, Issue 6. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the Review. Kassab M, Khriesat WM, Bawadi H, Anabrees J. Furosemide for transient tachypnoea of the newborn. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD003064. DOI: 10.1002/14651858.CD003064.pub2. (URL: http://dx.doi.org/10.1002/14651858.CD003064.pub2)

    Keywords

    • caesarean section
    • furosemide
    • newborn infants
    • tachypnoea
    • transient tachypnea of the newborn (TTN)

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