TY - JOUR
T1 - Global estimates on the number of people blind or visually impaired by glaucoma
T2 - a meta-analysis from 2000 to 2020
AU - Vision Loss Expert Group of the Global Burden of Disease Study
AU - GBD 2019 Blindness and Vision Impairment Collaborators
AU - Bourne, Rupert R.A.
AU - Jonas, Jost B.
AU - Friedman, David
AU - Nangia, Vinay
AU - Bron, Alain
AU - Tapply, Ian
AU - Fernandes, Arthur G.
AU - Cicinelli, Maria Vittoria
AU - Arrigo, Alessandro
AU - Leveziel, Nicolas
AU - Resnikoff, Serge
AU - Taylor, Hugh R.
AU - Sedighi, Tabassom
AU - Bikbov, Mukkharram M.
AU - Braithwaite, Tasanee
AU - Cheng, Ching Yu
AU - Congdon, Nathan
AU - Del Monte, Monte A.
AU - Ehrlich, Joshua R.
AU - Fricke, Tim
AU - Furtado, João M.
AU - Gazzard, Gus
AU - George, Ronnie
AU - Hartnett, M. Elizabeth
AU - Kahloun, Rim
AU - Kempen, John H.
AU - Khairallah, Moncef
AU - Khanna, Rohit C.
AU - Kim, Judy E.
AU - Lansingh, Van Charles
AU - Leasher, Janet
AU - Naidoo, Kovin S.
AU - Nowak, Michal
AU - Pesudovs, Konrad
AU - Peto, Tunde
AU - Ramulu, Pradeep
AU - Topouzis, Fotis
AU - Tsilimbaris, Mitiadis
AU - Wang, Ya Xing
AU - Wang, Ningli
AU - Flaxman, Seth
AU - Bourne, Rupert R.A.
AU - Jonas, Jost B.
AU - Casson, Robert James
AU - Friedman, David S.
AU - Nangia, Vinay
AU - Bron, Alain M.
AU - Tapply, Ian
AU - Naik, Ganesh R.
AU - Osuagwu, Uchechukwu Levi
N1 - Publisher Copyright:
© The Author(s) 2024.
PY - 2024/8
Y1 - 2024/8
N2 - Objectives: To estimate global and regional trends from 2000 to 2020 of the number of persons visually impaired by glaucoma and their proportion of the total number of vision-impaired individuals. Methods: A systematic review and meta-analysis of published population studies and grey literature from 2000 to 2020 was carried out to estimate global and regional trends in number of people with vision loss due to glaucoma. Moderate or severe vision loss (MSVI) was defined as visual acuity of 6/60 or better but <6/18 (moderate) and visual acuity of 3/60 or better but <6/60 (severe vision loss). Blindness was defined as presenting visual acuity <3/60. Results: Globally, in 2020, 3.61 million people were blind and nearly 4.14 million were visually impaired by glaucoma. Glaucoma accounted for 8.39% (95% uncertainty intervals [UIs]: 6.54, 10.29) of all blindness and 1.41% (95% UI: 1.10, 1.75) of all MSVI. Regionally, the highest proportion of blindness relating to glaucoma was found in high-income countries (26.12% [95% UI: 20.72, 32.09]), while the region with the highest age-standardized prevalence of glaucoma-related blindness and MSVI was Sub-Saharan Africa. Between 2000 and 2020, global age-standardized prevalence of glaucoma-related blindness among adults ≥50 years decreased by 26.06% among males (95% UI: 25.87, 26.24), and by 21.75% among females (95% UI: 21.54, 21.96), while MSVI due to glaucoma increased by 3.7% among males (95% UI: 3.42, 3.98), and by 7.3% in females (95% UI: 7.01, 7.59). Conclusions: Within the last two decades, glaucoma has remained a major cause of blindness globally and regionally.
AB - Objectives: To estimate global and regional trends from 2000 to 2020 of the number of persons visually impaired by glaucoma and their proportion of the total number of vision-impaired individuals. Methods: A systematic review and meta-analysis of published population studies and grey literature from 2000 to 2020 was carried out to estimate global and regional trends in number of people with vision loss due to glaucoma. Moderate or severe vision loss (MSVI) was defined as visual acuity of 6/60 or better but <6/18 (moderate) and visual acuity of 3/60 or better but <6/60 (severe vision loss). Blindness was defined as presenting visual acuity <3/60. Results: Globally, in 2020, 3.61 million people were blind and nearly 4.14 million were visually impaired by glaucoma. Glaucoma accounted for 8.39% (95% uncertainty intervals [UIs]: 6.54, 10.29) of all blindness and 1.41% (95% UI: 1.10, 1.75) of all MSVI. Regionally, the highest proportion of blindness relating to glaucoma was found in high-income countries (26.12% [95% UI: 20.72, 32.09]), while the region with the highest age-standardized prevalence of glaucoma-related blindness and MSVI was Sub-Saharan Africa. Between 2000 and 2020, global age-standardized prevalence of glaucoma-related blindness among adults ≥50 years decreased by 26.06% among males (95% UI: 25.87, 26.24), and by 21.75% among females (95% UI: 21.54, 21.96), while MSVI due to glaucoma increased by 3.7% among males (95% UI: 3.42, 3.98), and by 7.3% in females (95% UI: 7.01, 7.59). Conclusions: Within the last two decades, glaucoma has remained a major cause of blindness globally and regionally.
UR - https://www.scopus.com/pages/publications/85199541563
U2 - 10.1038/s41433-024-02995-5
DO - 10.1038/s41433-024-02995-5
M3 - Article
C2 - 38565601
AN - SCOPUS:85199541563
SN - 0950-222X
VL - 38
SP - 2036
EP - 2046
JO - Eye (Basingstoke)
JF - Eye (Basingstoke)
IS - 11
ER -