TY - JOUR
T1 - Global estimates on the number of people blind or visually impaired by diabetic retinopathy
T2 - a meta-analysis from 2000 to 2020
AU - Vision Loss Expert Group of the Global Burden of Disease Study
AU - the GBD 2019 Blindness and Vision Impairment Collaborators
AU - Curran, Katie
AU - Peto, Tunde
AU - Jonas, Jost B.
AU - Friedman, David
AU - Kim, Judy E.
AU - Leasher, Janet
AU - Tapply, Ian
AU - Fernandes, Arthur G.
AU - Cicinelli, Maria Vittoria
AU - Arrigo, Alessandro
AU - Leveziel, Nicolas
AU - Resnikoff, Serge
AU - Taylor, Hugh R.
AU - Sedighi, Tabassom
AU - Flaxman, Seth
AU - Bikbov, Mukkharram M.
AU - Braithwaite, Tasanee
AU - Bron, Alain
AU - Cheng, Ching Yu
AU - Del Monte, Monte A.
AU - Ehrlich, Joshua R.
AU - Furtado, João M.
AU - Gazzard, Gus
AU - Hartnett, M. Elizabeth
AU - Kahloun, Rim
AU - Kempen, John H.
AU - Khairallah, Moncef
AU - Khanna, Rohit C.
AU - Lansingh, Van Charles
AU - Naidoo, Kovin S.
AU - Nangia, Vinay
AU - Nowak, Michal
AU - Pesudovs, Konrad
AU - Ramulu, Pradeep
AU - Topouzis, Fotis
AU - Tsilimbaris, Mitiadis
AU - Wang, Ya Xing
AU - Wang, Ningli
AU - Bourne, Rupert R.A.
AU - Curran, Katie
AU - Peto, Tunde
AU - Bourne, Rupert
AU - Leasher, Janet L.
AU - Jonas, Jost B.
AU - Friedman, David S.
AU - Kim, Judy E.
AU - Fernandes, Arthur G.
AU - Ahinkorah, Bright Opoku
AU - Ahmadieh, Hamid
AU - Osuagwu, Uchechukwu Levi
PY - 2024/8
Y1 - 2024/8
N2 - Objectives: To estimate global and regional trends from 2000 to 2020 of the number of persons visually impaired by diabetic retinopathy and their proportion of the total number of vision-impaired individuals. Methods: Data from population-based studies on eye diseases between 1980 to 2018 were compiled. Meta-regression models were performed to estimate the prevalence of blindness (presenting visual acuity <3/60) and moderate or severe vision impairment (MSVI; <6/18 to ≥3/60) attributed to DR. The estimates, with 95% uncertainty intervals [UIs], were stratified by age, sex, year, and region. Results: In 2020, 1.07 million (95% UI: 0.76, 1.51) people were blind due to DR, with nearly 3.28 million (95% UI: 2.41, 4.34) experiencing MSVI. The GBD super-regions with the highest percentage of all DR-related blindness and MSVI were Latin America and the Caribbean (6.95% [95% UI: 5.08, 9.51]) and North Africa and the Middle East (2.12% [95% UI: 1.55, 2.79]), respectively. Between 2000 and 2020, changes in DR-related blindness and MSVI were greater among females than males, predominantly in the super-regions of South Asia (blindness) and Southeast Asia, East Asia, and Oceania (MSVI). Conclusions: Given the rapid global rise in diabetes and increased life expectancy, DR is anticipated to persist as a significant public health challenge. The findings emphasise the need for gender-specific interventions and region-specific DR healthcare policies to mitigate disparities and prevent avoidable blindness. This study contributes to the expanding body of literature on the burden of DR, highlighting the need for increased global attention and investment in this research area.
AB - Objectives: To estimate global and regional trends from 2000 to 2020 of the number of persons visually impaired by diabetic retinopathy and their proportion of the total number of vision-impaired individuals. Methods: Data from population-based studies on eye diseases between 1980 to 2018 were compiled. Meta-regression models were performed to estimate the prevalence of blindness (presenting visual acuity <3/60) and moderate or severe vision impairment (MSVI; <6/18 to ≥3/60) attributed to DR. The estimates, with 95% uncertainty intervals [UIs], were stratified by age, sex, year, and region. Results: In 2020, 1.07 million (95% UI: 0.76, 1.51) people were blind due to DR, with nearly 3.28 million (95% UI: 2.41, 4.34) experiencing MSVI. The GBD super-regions with the highest percentage of all DR-related blindness and MSVI were Latin America and the Caribbean (6.95% [95% UI: 5.08, 9.51]) and North Africa and the Middle East (2.12% [95% UI: 1.55, 2.79]), respectively. Between 2000 and 2020, changes in DR-related blindness and MSVI were greater among females than males, predominantly in the super-regions of South Asia (blindness) and Southeast Asia, East Asia, and Oceania (MSVI). Conclusions: Given the rapid global rise in diabetes and increased life expectancy, DR is anticipated to persist as a significant public health challenge. The findings emphasise the need for gender-specific interventions and region-specific DR healthcare policies to mitigate disparities and prevent avoidable blindness. This study contributes to the expanding body of literature on the burden of DR, highlighting the need for increased global attention and investment in this research area.
UR - http://www.scopus.com/inward/record.url?scp=85199813787&partnerID=8YFLogxK
U2 - 10.1038/s41433-024-03101-5
DO - 10.1038/s41433-024-03101-5
M3 - Article
C2 - 38937557
AN - SCOPUS:85199813787
SN - 0950-222X
VL - 38
SP - 2047
EP - 2057
JO - Eye (Basingstoke)
JF - Eye (Basingstoke)
IS - 11
ER -
