Abstract
Colorectal cancer (CRC) is the third most prevalent cancer and second in terms of mortality. Emerging evidence from recent studies suggests a potential role of Fusobacterium nucleatum in the development of CRC. In this article, we review studies from different geographical regions examining the association between F. nucleatum and CRC, the detection methods and the tumorigenic mechanisms. Furthermore, we discuss the potential clinical impact of F. nucleatum in CRC and suggest future study directions.
| Original language | English |
|---|---|
| Article number | 566 |
| Number of pages | 11 |
| Journal | Frontiers in Oncology |
| Volume | 9 |
| DOIs | |
| Publication status | Published - 2019 |
Open Access - Access Right Statement
© 2019 Lee, Liu, Riordan, Lee and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.Keywords
- bacteria
- cancer
- colon (anatomy)
- gastrointestinal system
