Global variation in anaphylaxis treatment: a scoping review protocol

Ayel Luis R. Batac; Andrew Wong-Pack; L. Mê-Linh; Justine Claire R. Reyes; Manvir K. Bhamra; Billy Hong; Laura Y. Feldman; Andrew T. Fong; Philippe Bégin

doi:10.1111/cea.70273

Global variation in anaphylaxis treatment: a scoping review protocol

Ayel Luis R. Batac
, Andrew Wong-Pack
, L. Mê-Linh
, Justine Claire R. Reyes
, Manvir K. Bhamra
, Billy Hong
, Laura Y. Feldman
, Andrew T. Fong
, Philippe Bégin

London School of Hygiene and Tropical Medicine
McMaster University
University of Toronto
University of Manitoba
Shoppers Drug Mart
Cancer Care Manitoba
The Children's Hospital at Westmead
Murdoch Children's Research Institute
University of Montreal
CHU Ste-Justine
Centre Hospitalier de L'Universite de Montreal

Research output: Contribution to journal › Article › peer-review

Abstract

Anaphylaxis is a rapidly progressive and potentially fatal allergic reaction that requires immediate treatment. International guidelines issued by the World Allergy Organization and the European Academy of Allergy and Clinical Immunology consistently recommend intramuscular adrenaline as the first-line therapy for anaphylaxis. Although these recommendations form a global consensus, recent analyses have noted that randomised controlled trials regarding the optimal route of adrenaline delivery are limited, highlighting the need to examine real world management practices more closely

Original language	English
Pages (from-to)	556-558
Number of pages	3
Journal	Clinical and Experimental Allergy
Volume	56
Issue number	5
DOIs	https://doi.org/10.1111/cea.70273
Publication status	Published - May 2026

Keywords

anaphylaxis
emergency treatment
global health
guideline adherence
treatment variation

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10.1111/cea.70273

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title = "Global variation in anaphylaxis treatment: a scoping review protocol",

abstract = "Anaphylaxis is a rapidly progressive and potentially fatal allergic reaction that requires immediate treatment. International guidelines issued by the World Allergy Organization and the European Academy of Allergy and Clinical Immunology consistently recommend intramuscular adrenaline as the first-line therapy for anaphylaxis. Although these recommendations form a global consensus, recent analyses have noted that randomised controlled trials regarding the optimal route of adrenaline delivery are limited, highlighting the need to examine real world management practices more closely",

keywords = "anaphylaxis, emergency treatment, global health, guideline adherence, treatment variation",

author = "Batac, \{Ayel Luis R.\} and Andrew Wong-Pack and L. M{\^e}-Linh and Reyes, \{Justine Claire R.\} and Bhamra, \{Manvir K.\} and Billy Hong and Feldman, \{Laura Y.\} and Fong, \{Andrew T.\} and Philippe B{\'e}gin",

year = "2026",

month = may,

doi = "10.1111/cea.70273",

language = "English",

volume = "56",

pages = "556--558",

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AU - Batac, Ayel Luis R.

AU - Wong-Pack, Andrew

AU - Mê-Linh, L.

AU - Reyes, Justine Claire R.

AU - Bhamra, Manvir K.

AU - Hong, Billy

AU - Feldman, Laura Y.

AU - Fong, Andrew T.

AU - Bégin, Philippe

PY - 2026/5

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N2 - Anaphylaxis is a rapidly progressive and potentially fatal allergic reaction that requires immediate treatment. International guidelines issued by the World Allergy Organization and the European Academy of Allergy and Clinical Immunology consistently recommend intramuscular adrenaline as the first-line therapy for anaphylaxis. Although these recommendations form a global consensus, recent analyses have noted that randomised controlled trials regarding the optimal route of adrenaline delivery are limited, highlighting the need to examine real world management practices more closely

AB - Anaphylaxis is a rapidly progressive and potentially fatal allergic reaction that requires immediate treatment. International guidelines issued by the World Allergy Organization and the European Academy of Allergy and Clinical Immunology consistently recommend intramuscular adrenaline as the first-line therapy for anaphylaxis. Although these recommendations form a global consensus, recent analyses have noted that randomised controlled trials regarding the optimal route of adrenaline delivery are limited, highlighting the need to examine real world management practices more closely

KW - anaphylaxis

KW - emergency treatment

KW - global health

KW - guideline adherence

KW - treatment variation

UR - https://www.scopus.com/pages/publications/105032115851

UR - https://go.openathens.net/redirector/westernsydney.edu.au?url=https://doi.org/10.1111/cea.70273

U2 - 10.1111/cea.70273

DO - 10.1111/cea.70273

M3 - Article

AN - SCOPUS:105032115851

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SP - 556

EP - 558

JO - Clinical and Experimental Allergy

JF - Clinical and Experimental Allergy

IS - 5

ER -

Global variation in anaphylaxis treatment: a scoping review protocol

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Keywords

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