Glycaemic control affects cellular sodium metabolism

D. Simmons, L. L. Ng, M. Harker, T. D.R. Hockaday

Research output: Contribution to journalArticlepeer-review

Abstract

Total and amiloride sensitive leucocyte sodium influx in media containing 10 mmol/l Na was studied directly using a triple isotope method for measuring initial 22Na uptake rates in 25 non insulin dependent diabetic subjects. Glycaemic control was assessed by glycated haemoglobin and fasting blood glucose. Although no significant relationship between Na flux and either plasma insulin or blood glucose could be found, glycated haemoglobin was significantly correlated with both total and amiloride sensitive flux. Glycaemic control must be considered in future work on cellular sodium metabolism.

Original languageEnglish
Pages (from-to)13-15
Number of pages3
JournalDiabetes research (Edinburgh, Lothian)
Volume10
Issue number1
Publication statusPublished - 1989
Externally publishedYes

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