TY - JOUR
T1 - Heterogeneity of Tregs and the complexity in the IL-12 cytokine family signaling in driving T-cell immune responses in atherosclerotic vessels
AU - Chistiakov, Dimitry A.
AU - Bobryshev, Yuri V.
AU - Orekhov, Alexander N.
PY - 2015
Y1 - 2015
N2 - The importance of immune inflammation in the development and progression of atherosclerotic lesions is well recognized. Accumulated evidence shows striking features of heterogeneity of regulatory T cells (Tregs) and the importance of the IL-12 cytokine family in regulation of Tregs in atherogenesis. The present review briefly summarized the current knowledge about the impact of the IL-12 cytokine family in regulation of immune processes in atherogenesis.
AB - The importance of immune inflammation in the development and progression of atherosclerotic lesions is well recognized. Accumulated evidence shows striking features of heterogeneity of regulatory T cells (Tregs) and the importance of the IL-12 cytokine family in regulation of Tregs in atherogenesis. The present review briefly summarized the current knowledge about the impact of the IL-12 cytokine family in regulation of immune processes in atherogenesis.
UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:41957
U2 - 10.1016/j.molimm.2015.01.013
DO - 10.1016/j.molimm.2015.01.013
M3 - Article
SN - 0161-5890
VL - 65
SP - 133
EP - 138
JO - Molecular Immunology
JF - Molecular Immunology
IS - 1
ER -