How viscous fingering can spoil your separation and you may not even suspect it

Ross A. Shalliker; Heather J. Catchpoole; Gary R. Dennis; Georges Guiochon

How viscous fingering can spoil your separation and you may not even suspect it

Ross A. Shalliker
, Heather J. Catchpoole
, Gary R. Dennis
, Georges Guiochon

School of Science

Research output: Contribution to journal › Article

Abstract

Techniques of both analytical and preparative liquid chromotography have advanced substantially in recent years. Nowadays, samples are often analyzed or purified in systems that incorporate one or more flow-stream changes from one mobile phase to another. It happens, for example, in column switching, in multidimensional separations, and in simulated moving bed (SMB) chromatography, where a feedstock stream enters continuously into a mobile-phase stream.

Original language	English
Number of pages	6
Journal	BioProcess International
Publication status	Published - 2007

Keywords

analytical and preparative liquid chromatography
mobile phase
multidimensional chromatography
stationary phase
viscosity
viscous fingering

Cite this

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title = "How viscous fingering can spoil your separation and you may not even suspect it",

abstract = "Techniques of both analytical and preparative liquid chromotography have advanced substantially in recent years. Nowadays, samples are often analyzed or purified in systems that incorporate one or more flow-stream changes from one mobile phase to another. It happens, for example, in column switching, in multidimensional separations, and in simulated moving bed (SMB) chromatography, where a feedstock stream enters continuously into a mobile-phase stream.",

keywords = "analytical and preparative liquid chromatography, mobile phase, multidimensional chromatography, stationary phase, viscosity, viscous fingering",

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AU - Catchpoole, Heather J.

AU - Dennis, Gary R.

AU - Guiochon, Georges

PY - 2007

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N2 - Techniques of both analytical and preparative liquid chromotography have advanced substantially in recent years. Nowadays, samples are often analyzed or purified in systems that incorporate one or more flow-stream changes from one mobile phase to another. It happens, for example, in column switching, in multidimensional separations, and in simulated moving bed (SMB) chromatography, where a feedstock stream enters continuously into a mobile-phase stream.

AB - Techniques of both analytical and preparative liquid chromotography have advanced substantially in recent years. Nowadays, samples are often analyzed or purified in systems that incorporate one or more flow-stream changes from one mobile phase to another. It happens, for example, in column switching, in multidimensional separations, and in simulated moving bed (SMB) chromatography, where a feedstock stream enters continuously into a mobile-phase stream.

KW - analytical and preparative liquid chromatography

KW - mobile phase

KW - multidimensional chromatography

KW - stationary phase

KW - viscosity

KW - viscous fingering

UR - http://handle.uws.edu.au:8081/1959.7/36464

M3 - Article

SN - 1542-6319

JO - BioProcess International

JF - BioProcess International

ER -

How viscous fingering can spoil your separation and you may not even suspect it

Abstract

Keywords

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