Human population history at the crossroads of East and Southeast Asia since 11,000 years ago

Tianyi Wang; Wei Wang; Guangmao Xie; Zhen Li; Xuechun Fan; Qingping Yang; Xichao Wu; Peng Cao; Yichen Liu; Ruowei Yang; Feng Liu; Qingyan Dai; Xiaotian Feng; Xiaohong Wu; Ling Qin; Fajun Li; Wanjing Ping; Lizhao Zhang; Ming Zhang; Yalin Liu; Xiaoshan Chen; Dongju Zhang; Zhenyu Zhou; Yun Wu; Hassan Shafiey; Xing Gao; Darren Curnoe; Xiaowei Mao; E. Andrew Bennett; Xueping Ji; Melinda A. Yang; Qiaomei Fu

doi:10.1016/j.cell.2021.05.018

Human population history at the crossroads of East and Southeast Asia since 11,000 years ago

Tianyi Wang
, Wei Wang
, Guangmao Xie
, Zhen Li
, Xuechun Fan
, Qingping Yang
, Xichao Wu
, Peng Cao
, Yichen Liu
, Ruowei Yang
, Feng Liu
, Qingyan Dai
, Xiaotian Feng
, Xiaohong Wu
, Ling Qin
, Fajun Li
, Wanjing Ping
, Lizhao Zhang
, Ming Zhang
, Yalin Liu

Xiaoshan Chen, Dongju Zhang, Zhenyu Zhou, Yun Wu, Hassan Shafiey, Xing Gao, Darren Curnoe, Xiaowei Mao, E. Andrew Bennett, Xueping Ji, Melinda A. Yang, Qiaomei Fu

Research output: Contribution to journal › Article › peer-review

131 Citations (Scopus)

Abstract

Past human genetic diversity and migration between southern China and Southeast Asia have not been well characterized, in part due to poor preservation of ancient DNA in hot and humid regions. We sequenced 31 ancient genomes from southern China (Guangxi and Fujian), including two ∼12,000- to 10,000-year-old individuals representing the oldest humans sequenced from southern China. We discovered a deeply diverged East Asian ancestry in the Guangxi region that persisted until at least 6,000 years ago. We found that ∼9,000- to 6,000-year-old Guangxi populations were a mixture of local ancestry, southern ancestry previously sampled in Fujian, and deep Asian ancestry related to Southeast Asian Hòabìnhian hunter-gatherers, showing broad admixture in the region predating the appearance of farming. Historical Guangxi populations dating to ∼1,500 to 500 years ago are closely related to Tai-Kadai and Hmong-Mien speakers. Our results show heavy interactions among three distinct ancestries at the crossroads of East and Southeast Asia.

Original language	English
Pages (from-to)	3829-3841.e21
Number of pages	35
Journal	Cell
Volume	184
Issue number	14
DOIs	https://doi.org/10.1016/j.cell.2021.05.018
Publication status	Published - Jul 2021
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 2 Zero Hunger

Keywords

12,000-year-old humans
admixture
ancient DNA
cross-interactions
deeply diverged ancestry
pre-farming

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10.1016/j.cell.2021.05.018

Cite this

@article{89869a15ff8f41bf8b2336b28568b614,

title = "Human population history at the crossroads of East and Southeast Asia since 11,000 years ago",

abstract = "Past human genetic diversity and migration between southern China and Southeast Asia have not been well characterized, in part due to poor preservation of ancient DNA in hot and humid regions. We sequenced 31 ancient genomes from southern China (Guangxi and Fujian), including two ∼12,000- to 10,000-year-old individuals representing the oldest humans sequenced from southern China. We discovered a deeply diverged East Asian ancestry in the Guangxi region that persisted until at least 6,000 years ago. We found that ∼9,000- to 6,000-year-old Guangxi populations were a mixture of local ancestry, southern ancestry previously sampled in Fujian, and deep Asian ancestry related to Southeast Asian H{\`o}ab{\`i}nhian hunter-gatherers, showing broad admixture in the region predating the appearance of farming. Historical Guangxi populations dating to ∼1,500 to 500 years ago are closely related to Tai-Kadai and Hmong-Mien speakers. Our results show heavy interactions among three distinct ancestries at the crossroads of East and Southeast Asia.",

keywords = "12,000-year-old humans, admixture, ancient DNA, cross-interactions, deeply diverged ancestry, pre-farming",

author = "Tianyi Wang and Wei Wang and Guangmao Xie and Zhen Li and Xuechun Fan and Qingping Yang and Xichao Wu and Peng Cao and Yichen Liu and Ruowei Yang and Feng Liu and Qingyan Dai and Xiaotian Feng and Xiaohong Wu and Ling Qin and Fajun Li and Wanjing Ping and Lizhao Zhang and Ming Zhang and Yalin Liu and Xiaoshan Chen and Dongju Zhang and Zhenyu Zhou and Yun Wu and Hassan Shafiey and Xing Gao and Darren Curnoe and Xiaowei Mao and Bennett, \{E. Andrew\} and Xueping Ji and Yang, \{Melinda A.\} and Qiaomei Fu",

year = "2021",

month = jul,

doi = "10.1016/j.cell.2021.05.018",

language = "English",

volume = "184",

pages = "3829--3841.e21",

journal = "Cell",

issn = "0092-8674",

publisher = "Elsevier B.V.",

number = "14",

}

Wang, T, Wang, W, Xie, G, Li, Z, Fan, X, Yang, Q, Wu, X, Cao, P, Liu, Y, Yang, R, Liu, F, Dai, Q, Feng, X, Wu, X, Qin, L, Li, F, Ping, W, Zhang, L, Zhang, M, Liu, Y, Chen, X, Zhang, D, Zhou, Z, Wu, Y, Shafiey, H, Gao, X, Curnoe, D, Mao, X, Bennett, EA, Ji, X, Yang, MA & Fu, Q 2021, 'Human population history at the crossroads of East and Southeast Asia since 11,000 years ago', Cell, vol. 184, no. 14, pp. 3829-3841.e21. https://doi.org/10.1016/j.cell.2021.05.018

TY - JOUR

T1 - Human population history at the crossroads of East and Southeast Asia since 11,000 years ago

AU - Wang, Tianyi

AU - Wang, Wei

AU - Xie, Guangmao

AU - Li, Zhen

AU - Fan, Xuechun

AU - Yang, Qingping

AU - Wu, Xichao

AU - Cao, Peng

AU - Liu, Yichen

AU - Yang, Ruowei

AU - Liu, Feng

AU - Dai, Qingyan

AU - Feng, Xiaotian

AU - Wu, Xiaohong

AU - Qin, Ling

AU - Li, Fajun

AU - Ping, Wanjing

AU - Zhang, Lizhao

AU - Zhang, Ming

AU - Liu, Yalin

AU - Chen, Xiaoshan

AU - Zhang, Dongju

AU - Zhou, Zhenyu

AU - Wu, Yun

AU - Shafiey, Hassan

AU - Gao, Xing

AU - Curnoe, Darren

AU - Mao, Xiaowei

AU - Bennett, E. Andrew

AU - Ji, Xueping

AU - Yang, Melinda A.

AU - Fu, Qiaomei

PY - 2021/7

Y1 - 2021/7

N2 - Past human genetic diversity and migration between southern China and Southeast Asia have not been well characterized, in part due to poor preservation of ancient DNA in hot and humid regions. We sequenced 31 ancient genomes from southern China (Guangxi and Fujian), including two ∼12,000- to 10,000-year-old individuals representing the oldest humans sequenced from southern China. We discovered a deeply diverged East Asian ancestry in the Guangxi region that persisted until at least 6,000 years ago. We found that ∼9,000- to 6,000-year-old Guangxi populations were a mixture of local ancestry, southern ancestry previously sampled in Fujian, and deep Asian ancestry related to Southeast Asian Hòabìnhian hunter-gatherers, showing broad admixture in the region predating the appearance of farming. Historical Guangxi populations dating to ∼1,500 to 500 years ago are closely related to Tai-Kadai and Hmong-Mien speakers. Our results show heavy interactions among three distinct ancestries at the crossroads of East and Southeast Asia.

AB - Past human genetic diversity and migration between southern China and Southeast Asia have not been well characterized, in part due to poor preservation of ancient DNA in hot and humid regions. We sequenced 31 ancient genomes from southern China (Guangxi and Fujian), including two ∼12,000- to 10,000-year-old individuals representing the oldest humans sequenced from southern China. We discovered a deeply diverged East Asian ancestry in the Guangxi region that persisted until at least 6,000 years ago. We found that ∼9,000- to 6,000-year-old Guangxi populations were a mixture of local ancestry, southern ancestry previously sampled in Fujian, and deep Asian ancestry related to Southeast Asian Hòabìnhian hunter-gatherers, showing broad admixture in the region predating the appearance of farming. Historical Guangxi populations dating to ∼1,500 to 500 years ago are closely related to Tai-Kadai and Hmong-Mien speakers. Our results show heavy interactions among three distinct ancestries at the crossroads of East and Southeast Asia.

KW - 12,000-year-old humans

KW - admixture

KW - ancient DNA

KW - cross-interactions

KW - deeply diverged ancestry

KW - pre-farming

UR - https://www.scopus.com/pages/publications/85109006438

UR - https://go.openathens.net/redirector/westernsydney.edu.au?url=https://doi.org/10.1016/j.cell.2021.05.018

U2 - 10.1016/j.cell.2021.05.018

DO - 10.1016/j.cell.2021.05.018

M3 - Article

C2 - 34171307

AN - SCOPUS:85109006438

SN - 0092-8674

VL - 184

SP - 3829-3841.e21

JO - Cell

JF - Cell

IS - 14

ER -

Human population history at the crossroads of East and Southeast Asia since 11,000 years ago

Abstract

UN SDGs

Keywords

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