Hypoglycemic and insulin release effects of Hugonia mystax leaves in rabbits

S. Nammi, S. S. Ganti, D. S. Lodagala, B. S.R. Babu

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

The ethanolic extract of Hugonia mystax leaves was tested for its hypoglycemic and insulin releasing properties in normal and diabetic rabbits. Blood glucose levels were determined after treatment with the extract at doses of 100, 200 and 300 mg/kg. Significant reductions in blood levels were observed in both normal and diabetic rabbits while an appreciable rise in serum insulin was also observed in diabetic rabbits compared to control animals. These results suggest that the reduction in blood glucose produced by the extract is through insulin secretion.

Original languageEnglish
Pages (from-to)1-3
Number of pages3
JournalAsia Pacific Journal of Pharmacology
Volume16
Issue number1
Publication statusPublished - Mar 2003
Externally publishedYes

Keywords

  • Blood glucose
  • Diabetes mellitus
  • Glucose uptake
  • Hugonia mystax
  • Serum insulin

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