IDF Diabetes Atlas : the prevalence of pre-existing diabetes in pregnancy : a systematic review and meta-analysis of studies published during 2010-2020

Tawanda Chivese, Cecilia A. Hoegfeldt, Mahmoud Werfalli, Lili Yuen, Hong Sun, Suvi Karuranga, Ninghua Li, Akhil Gupta, Jincy Immanuel, Hema Divakar, Camille E. Powe, Naomi S. Levitt, Xilin Yang, David Simmons

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)

Abstract

Objectives: To estimate the prevalence of pre-existing diabetes in pregnancy from studies published during 2010-2020. Methods: We searched PubMed, CINAHL, Scopus and other sources for relevant data sources. The prevalence of overall pre-existing, type 1 and type 2 diabetes, by country, region and period of study was synthesised from included studies using the inverse-variance heterogeneity model and the Freeman-Tukey transformation. Heterogeneity was assessed using the I2 statistic and publication bias using funnel plots. Results: We identified 2479 records, of which 42 data sources with a total of 78 943 376 women, met the eligibility criteria. The included studies were from 17 countries in North America, Europe, the Middle East and North Africa, Australasia, Asia and Africa. The lowest prevalence was in Europe (0.5%, 95 %CI 0.4-0.7) and the highest in the Middle East and North Africa (2.4%, 95 %CI 1.5-3.1). The prevalence of pre-existing diabetes doubled from 0.5% (95 %CI 0.1-1.0) to 1.0% (95 %CI 0.6-1.5) during the period 1990-2020. The pooled prevalences of pre-existing type 1 and type 2 diabetes were 0.3% (95 %CI 0.2-0.4) and 0.2% (95 %CI 0.0-0.9) respectively. Conclusion: While the prevalence of pre-existing diabetes in pregnancy is low, it has doubled from 1990 to 2020.
Original languageEnglish
Article number109049
Number of pages10
JournalDiabetes Research and Clinical Practice
Volume183
DOIs
Publication statusPublished - 2022

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