In vivo studies of a platinum(II) metallointercalator

Dianne M. Fisher; Ronald R. Fenton; Janice R. Aldrich-Wright

doi:10.1039/b811723c

In vivo studies of a platinum(II) metallointercalator

Dianne M. Fisher, Ronald R. Fenton, Janice R. Aldrich-Wright

School of Science

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

An in vivo study for determining the toxicity and efficacy of [Pt(S,S-dach)(phen)Cl2Â·1.5H2OÂ·0.5HCl (PHENSS) in female Specific Pathogen Free (SPF) Swiss nude mice bearing PC3 tumour xenografts revealed PHENSS to be non-toxic and effective in decreasing tumour growth.

Original language	English
Pages (from-to)	5613-5615
Number of pages	3
Journal	Chemical Communications
Volume	43
DOIs	https://doi.org/10.1039/b811723c
Publication status	Published - 2008

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10.1039/b811723c

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title = "In vivo studies of a platinum(II) metallointercalator",

abstract = "An in vivo study for determining the toxicity and efficacy of [Pt(S,S-dach)(phen)Cl2{\^A}·1.5H2O{\^A}·0.5HCl (PHENSS) in female Specific Pathogen Free (SPF) Swiss nude mice bearing PC3 tumour xenografts revealed PHENSS to be non-toxic and effective in decreasing tumour growth.",

author = "Fisher, {Dianne M.} and Fenton, {Ronald R.} and Aldrich-Wright, {Janice R.}",

year = "2008",

doi = "10.1039/b811723c",

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AU - Fisher, Dianne M.

AU - Fenton, Ronald R.

AU - Aldrich-Wright, Janice R.

PY - 2008

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AB - An in vivo study for determining the toxicity and efficacy of [Pt(S,S-dach)(phen)Cl2Â·1.5H2OÂ·0.5HCl (PHENSS) in female Specific Pathogen Free (SPF) Swiss nude mice bearing PC3 tumour xenografts revealed PHENSS to be non-toxic and effective in decreasing tumour growth.

UR - http://handle.uws.edu.au:8081/1959.7/555143

U2 - 10.1039/b811723c

DO - 10.1039/b811723c

M3 - Article

C2 - 18997969

SN - 1359-7345

VL - 43

SP - 5613

EP - 5615

JO - Chemical Communications

JF - Chemical Communications

ER -

In vivo studies of a platinum(II) metallointercalator

Abstract

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