Innovative pharmacologic approaches to eating disorder treatment

Aaron Keshen; Stephen Touyz; Emilie Lacroix; Phillipa Hay; Susan L. McElroy

doi:10.1016/j.psc.2025.08.014

Innovative pharmacologic approaches to eating disorder treatment

Aaron Keshen, Stephen Touyz, Emilie Lacroix, Phillipa Hay, Susan L. McElroy

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Eating disorders, including anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), and avoidant/restrictive food intake disorder (ARFID) are complex psychiatric conditions characterized by severe disturbances in eating behaviors and associated psychological distress. These disorders often co-occur with medical complications, psychiatric comorbidities, and functional impairments, leading to an impact on quality of life and increased mortality rates. Despite their high prevalence and substantial burden, treatment outcomes for eating disorders remain suboptimal.

Original language	English
Number of pages	14
Journal	Psychiatric Clinics of North America
DOIs	https://doi.org/10.1016/j.psc.2025.08.014
Publication status	E-pub ahead of print (In Press) - 2025

Keywords

Anorexia nervosa
Avoidant/restrictive food intake disorder
Binge-eating disorder
Bulimia nervosa
Eating disorders
Pharmacotherapy
Psychedelics
Stimulant medications

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10.1016/j.psc.2025.08.014

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title = "Innovative pharmacologic approaches to eating disorder treatment",

abstract = "Eating disorders, including anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), and avoidant/restrictive food intake disorder (ARFID) are complex psychiatric conditions characterized by severe disturbances in eating behaviors and associated psychological distress. These disorders often co-occur with medical complications, psychiatric comorbidities, and functional impairments, leading to an impact on quality of life and increased mortality rates. Despite their high prevalence and substantial burden, treatment outcomes for eating disorders remain suboptimal.",

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AU - Touyz, Stephen

AU - Lacroix, Emilie

AU - Hay, Phillipa

AU - McElroy, Susan L.

PY - 2025

Y1 - 2025

N2 - Eating disorders, including anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), and avoidant/restrictive food intake disorder (ARFID) are complex psychiatric conditions characterized by severe disturbances in eating behaviors and associated psychological distress. These disorders often co-occur with medical complications, psychiatric comorbidities, and functional impairments, leading to an impact on quality of life and increased mortality rates. Despite their high prevalence and substantial burden, treatment outcomes for eating disorders remain suboptimal.

AB - Eating disorders, including anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), and avoidant/restrictive food intake disorder (ARFID) are complex psychiatric conditions characterized by severe disturbances in eating behaviors and associated psychological distress. These disorders often co-occur with medical complications, psychiatric comorbidities, and functional impairments, leading to an impact on quality of life and increased mortality rates. Despite their high prevalence and substantial burden, treatment outcomes for eating disorders remain suboptimal.

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KW - Avoidant/restrictive food intake disorder

KW - Binge-eating disorder

KW - Bulimia nervosa

KW - Eating disorders

KW - Pharmacotherapy

KW - Psychedelics

KW - Stimulant medications

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DO - 10.1016/j.psc.2025.08.014

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SN - 0193-953X

JO - Psychiatric Clinics of North America

JF - Psychiatric Clinics of North America

ER -

Innovative pharmacologic approaches to eating disorder treatment

Abstract

Keywords

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