Interaction of 4-hydroxynonenal-modified low-density lipoproteins with the fibroblast apoliprotein B/E receptor

W. Jessup; G. Jurgens; J. Lang; H. Esterbauer; R. T. Dean

doi:10.1042/bj2340245

Interaction of 4-hydroxynonenal-modified low-density lipoproteins with the fibroblast apoliprotein B/E receptor

W. Jessup
, G. Jurgens
, J. Lang
, H. Esterbauer
, R. T. Dean

Brunel University London
Unknown

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

The incorporation of the lipid peroxidation product 4-hydroxynonenal into low-density lipoprotein (LDL) increases the negative charge of the particle, and decreases its affinity for the fibroblast LDL receptor. It is suggested that this modification may occur in vivo, and might promote atherogenesis.

Original language	English
Pages (from-to)	245-248
Number of pages	4
Journal	The Biochemical Journal
Volume	234
Issue number	1
DOIs	https://doi.org/10.1042/bj2340245
Publication status	Published - 1986
Externally published	Yes

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title = "Interaction of 4-hydroxynonenal-modified low-density lipoproteins with the fibroblast apoliprotein B/E receptor",

abstract = "The incorporation of the lipid peroxidation product 4-hydroxynonenal into low-density lipoprotein (LDL) increases the negative charge of the particle, and decreases its affinity for the fibroblast LDL receptor. It is suggested that this modification may occur in vivo, and might promote atherogenesis.",

author = "W. Jessup and G. Jurgens and J. Lang and H. Esterbauer and Dean, \{R. T.\}",

year = "1986",

doi = "10.1042/bj2340245",

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journal = "The Biochemical Journal",

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T1 - Interaction of 4-hydroxynonenal-modified low-density lipoproteins with the fibroblast apoliprotein B/E receptor

AU - Jessup, W.

AU - Jurgens, G.

AU - Lang, J.

AU - Esterbauer, H.

AU - Dean, R. T.

PY - 1986

Y1 - 1986

N2 - The incorporation of the lipid peroxidation product 4-hydroxynonenal into low-density lipoprotein (LDL) increases the negative charge of the particle, and decreases its affinity for the fibroblast LDL receptor. It is suggested that this modification may occur in vivo, and might promote atherogenesis.

AB - The incorporation of the lipid peroxidation product 4-hydroxynonenal into low-density lipoprotein (LDL) increases the negative charge of the particle, and decreases its affinity for the fibroblast LDL receptor. It is suggested that this modification may occur in vivo, and might promote atherogenesis.

UR - https://www.scopus.com/pages/publications/0022509762

U2 - 10.1042/bj2340245

DO - 10.1042/bj2340245

M3 - Article

AN - SCOPUS:0022509762

SN - 0264-6021

VL - 234

SP - 245

EP - 248

JO - The Biochemical Journal

JF - The Biochemical Journal

IS - 1

ER -

Interaction of 4-hydroxynonenal-modified low-density lipoproteins with the fibroblast apoliprotein B/E receptor

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