TY - JOUR
T1 - Interventions, outcomes and outcome measurement instruments in stillbirth care research
T2 - a systematic review to inform the development of a core outcome set
AU - Bakhbakhi, Danya
AU - Siassakos, Dimitrios
AU - Davies, Anna
AU - Merriel, Abi
AU - Barnard, Katie
AU - Stead, Emma
AU - Shakespeare, Clare
AU - Duffy, James M.N.
AU - Hinton, Lisa
AU - McDowell, Karolina
AU - Lyons, Anna
AU - Fraser, Abigail
AU - Burden, Christy
AU - iCHOOSE Collaborative Group,
AU - Downe, Soo
AU - et al.,
PY - 2023/5
Y1 - 2023/5
N2 - Background: A core outcome set could address inconsistent outcome reporting and improve evidence for stillbirth care research, which have been identified as an important research priority. Objectives: To identify outcomes and outcome measurement instruments reported by studies evaluating interventions after the diagnosis of a stillbirth. Search strategy: Amed, BNI, CINAHL, ClinicalTrials.gov, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Embase, MEDLINE, PsycINFO, and WHO ICTRP from 1998 to August 2021. Selection criteria: Randomised and non-randomised comparative or non-comparative studies reporting a stillbirth care intervention. Data collection and analysis: Interventions, outcomes reported, definitions and outcome measurement tools were extracted. Main results: Forty randomised and 200 non-randomised studies were included. Fifty-eight different interventions were reported, labour and birth care (52 studies), hospital bereavement care (28 studies), clinical investigations (116 studies), care in a multiple pregnancy (2 studies), psychosocial support (28 studies) and care in a subsequent pregnancy (14 studies). A total of 391 unique outcomes were reported and organised into 14 outcome domains: labour and birth; postpartum; delivery of care; investigations; multiple pregnancy; mental health; emotional functioning; grief and bereavement; social functioning; relationship; whole person; subsequent pregnancy; subsequent children and siblings and economic. A total of 242 outcome measurement instruments were used, with 0-22 tools per outcome. Conclusions: Heterogeneity in outcome reporting, outcome definition and measurement tools in care after stillbirth exists. Considerable research gaps on specific intervention types in stillbirth care were identified. A core outcome set is needed to standardise outcome collection and reporting for stillbirth care research.
AB - Background: A core outcome set could address inconsistent outcome reporting and improve evidence for stillbirth care research, which have been identified as an important research priority. Objectives: To identify outcomes and outcome measurement instruments reported by studies evaluating interventions after the diagnosis of a stillbirth. Search strategy: Amed, BNI, CINAHL, ClinicalTrials.gov, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Embase, MEDLINE, PsycINFO, and WHO ICTRP from 1998 to August 2021. Selection criteria: Randomised and non-randomised comparative or non-comparative studies reporting a stillbirth care intervention. Data collection and analysis: Interventions, outcomes reported, definitions and outcome measurement tools were extracted. Main results: Forty randomised and 200 non-randomised studies were included. Fifty-eight different interventions were reported, labour and birth care (52 studies), hospital bereavement care (28 studies), clinical investigations (116 studies), care in a multiple pregnancy (2 studies), psychosocial support (28 studies) and care in a subsequent pregnancy (14 studies). A total of 391 unique outcomes were reported and organised into 14 outcome domains: labour and birth; postpartum; delivery of care; investigations; multiple pregnancy; mental health; emotional functioning; grief and bereavement; social functioning; relationship; whole person; subsequent pregnancy; subsequent children and siblings and economic. A total of 242 outcome measurement instruments were used, with 0-22 tools per outcome. Conclusions: Heterogeneity in outcome reporting, outcome definition and measurement tools in care after stillbirth exists. Considerable research gaps on specific intervention types in stillbirth care were identified. A core outcome set is needed to standardise outcome collection and reporting for stillbirth care research.
KW - core outcome set
KW - patient and public involvement
KW - stillbirth
KW - stillbirth care
KW - systematic review
UR - http://www.scopus.com/inward/record.url?scp=85152430906&partnerID=8YFLogxK
U2 - 10.1111/1471-0528.17390
DO - 10.1111/1471-0528.17390
M3 - Article
C2 - 36655361
AN - SCOPUS:85152430906
SN - 1470-0328
VL - 130
SP - 560
EP - 576
JO - BJOG : An International Journal of Obstetrics and Gynaecology
JF - BJOG : An International Journal of Obstetrics and Gynaecology
IS - 6
ER -
