Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance

Dimitry A. Chistiakov; Yuri V. Bobryshev; Emil Kozarov; Igor A. Sobenin; Alexander N. Orekhov

doi:10.3389/fmicb.2014.00781

Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance

Dimitry A. Chistiakov
, Yuri V. Bobryshev
, Emil Kozarov
, Igor A. Sobenin
, Alexander N. Orekhov

Research output: Contribution to journal › Article › peer-review

72 Citations (Scopus)

Abstract

The mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. This review provides current information about mechanisms of induction of mucosal tolerance and about impact of gut microbiota to mucosal tolerance.

Original language	English
Article number	781
Number of pages	9
Journal	Frontiers in Microbiology
Volume	5
DOIs	https://doi.org/10.3389/fmicb.2014.00781
Publication status	Published - 2015

Keywords

immunology
infections
mucous membrane

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10.3389/fmicb.2014.00781

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title = "Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance",

abstract = "The mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. This review provides current information about mechanisms of induction of mucosal tolerance and about impact of gut microbiota to mucosal tolerance.",

keywords = "immunology, infections, mucous membrane",

author = "Chistiakov, \{Dimitry A.\} and Bobryshev, \{Yuri V.\} and Emil Kozarov and Sobenin, \{Igor A.\} and Orekhov, \{Alexander N.\}",

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AU - Chistiakov, Dimitry A.

AU - Bobryshev, Yuri V.

AU - Kozarov, Emil

AU - Sobenin, Igor A.

AU - Orekhov, Alexander N.

PY - 2015

Y1 - 2015

N2 - The mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. This review provides current information about mechanisms of induction of mucosal tolerance and about impact of gut microbiota to mucosal tolerance.

AB - The mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. This review provides current information about mechanisms of induction of mucosal tolerance and about impact of gut microbiota to mucosal tolerance.

KW - immunology

KW - infections

KW - mucous membrane

UR - http://handle.uws.edu.au:8081/1959.7/564418

U2 - 10.3389/fmicb.2014.00781

DO - 10.3389/fmicb.2014.00781

M3 - Article

SN - 1664-302X

VL - 5

JO - Frontiers in Microbiology

JF - Frontiers in Microbiology

M1 - 781

ER -

Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance

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