Investigating the biological significance of metallointercalators with cDNA microarrays

Elise P. Wright; Victoria Lyons; Shaoyu Wang; Vincent J. Higgins

Investigating the biological significance of metallointercalators with cDNA microarrays

Elise P. Wright, Victoria Lyons, Shaoyu Wang, Vincent J. Higgins

Research output: Chapter in Book / Conference Paper › Chapter

Abstract

The double helix coded sequence of nucleotide bases with its protective sugar phosphate backbone forms deoxyribonucleic acid (DNA) which is the genetic blueprint of all living things. All the information required for the development, operation and maintenance of cells is contained in a sequence of adenine (A), thymine (T), cytosine (C) and guanine (G) bases, where adenine is paired with thymine and cytosine is paired with guanine [1]. The DNA sequence is made usable by transcription of the nucleotide sequence into single stranded messenger RNA (mRNA). This means that the four member nucleic acid base code sequence is converted into a 22 member amino acid code [2].

Original language	English
Title of host publication	Metallointercalators: Synthesis and Techniques to Probe Their Interactions with Biomolecules
Editors	Janice R. Aldrich-Wright
Place of Publication	U.S.
Publisher	Springer
Pages	325-359
Number of pages	35
ISBN (Electronic)	9783211990797
ISBN (Print)	9783211094273
Publication status	Published - 2011

Cite this

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title = "Investigating the biological significance of metallointercalators with cDNA microarrays",

abstract = "The double helix coded sequence of nucleotide bases with its protective sugar phosphate backbone forms deoxyribonucleic acid (DNA) which is the genetic blueprint of all living things. All the information required for the development, operation and maintenance of cells is contained in a sequence of adenine (A), thymine (T), cytosine (C) and guanine (G) bases, where adenine is paired with thymine and cytosine is paired with guanine [1]. The DNA sequence is made usable by transcription of the nucleotide sequence into single stranded messenger RNA (mRNA). This means that the four member nucleic acid base code sequence is converted into a 22 member amino acid code [2].",

author = "Wright, {Elise P.} and Victoria Lyons and Shaoyu Wang and Higgins, {Vincent J.}",

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T1 - Investigating the biological significance of metallointercalators with cDNA microarrays

AU - Wright, Elise P.

AU - Lyons, Victoria

AU - Wang, Shaoyu

AU - Higgins, Vincent J.

PY - 2011

Y1 - 2011

N2 - The double helix coded sequence of nucleotide bases with its protective sugar phosphate backbone forms deoxyribonucleic acid (DNA) which is the genetic blueprint of all living things. All the information required for the development, operation and maintenance of cells is contained in a sequence of adenine (A), thymine (T), cytosine (C) and guanine (G) bases, where adenine is paired with thymine and cytosine is paired with guanine [1]. The DNA sequence is made usable by transcription of the nucleotide sequence into single stranded messenger RNA (mRNA). This means that the four member nucleic acid base code sequence is converted into a 22 member amino acid code [2].

AB - The double helix coded sequence of nucleotide bases with its protective sugar phosphate backbone forms deoxyribonucleic acid (DNA) which is the genetic blueprint of all living things. All the information required for the development, operation and maintenance of cells is contained in a sequence of adenine (A), thymine (T), cytosine (C) and guanine (G) bases, where adenine is paired with thymine and cytosine is paired with guanine [1]. The DNA sequence is made usable by transcription of the nucleotide sequence into single stranded messenger RNA (mRNA). This means that the four member nucleic acid base code sequence is converted into a 22 member amino acid code [2].

UR - http://handle.uws.edu.au:8081/1959.7/543865

UR - http://link.springer.com/book/10.1007%2F978-3-211-99079-7

M3 - Chapter

SN - 9783211094273

SP - 325

EP - 359

BT - Metallointercalators: Synthesis and Techniques to Probe Their Interactions with Biomolecules

A2 - Aldrich-Wright, Janice R.

PB - Springer

CY - U.S.

ER -

Investigating the biological significance of metallointercalators with cDNA microarrays

Abstract

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