Lactose : polymorphism, caking behaviour and use in pharmaceuticals

Yuanita D. Listiohadi; Jim Hourigan; Robert J. Steele; R. L. Johnson; Robert W. Sleigh

Lactose : polymorphism, caking behaviour and use in pharmaceuticals

Yuanita D. Listiohadi, Jim Hourigan, Robert J. Steele, R. L. Johnson, Robert W. Sleigh

Research output: Chapter in Book / Conference Paper › Conference Paper

Abstract

![CDATA[Lactose is an important ingredient used by the pharmaceutical industry, which is one of the largest consumers of the highly purified grades of this saccharide. Although the usual commercial product is crystalline a-lactose monohydrate, many users are unaware that lactose exists in numerous polymorphic and isomeric forms, each form possessing a range of unique particle characteristics such as flowability, compactibility, hygroscopicity, solubility, and shelf life (e.g. tendency to cake). Not all of these characteristics have been fully exploited by the pharmaceutical industry. This paper reports on work directed to better understanding how the characteristics of lactose particles affect their functional qualities.]]

Original language	English
Title of host publication	World Congress on Particle Technology 4: Proceedings of the Symposium held in Sydney, N.S.W., 21-25 July, 2002
Publisher	The Technical Committee
Number of pages	1
ISBN (Print)	0858257947
Publication status	Published - 2002
Event	World Congress on Particle Technology - Duration: 1 Jan 2002 → …

Conference

Conference	World Congress on Particle Technology
Period	1/01/02 → …

Keywords

lactose
drugs
saccharides
morphology

Cite this

@inproceedings{038e5e33952f4f9c94a9e6596d97b63c,

title = "Lactose : polymorphism, caking behaviour and use in pharmaceuticals",

abstract = "![CDATA[Lactose is an important ingredient used by the pharmaceutical industry, which is one of the largest consumers of the highly purified grades of this saccharide. Although the usual commercial product is crystalline a-lactose monohydrate, many users are unaware that lactose exists in numerous polymorphic and isomeric forms, each form possessing a range of unique particle characteristics such as flowability, compactibility, hygroscopicity, solubility, and shelf life (e.g. tendency to cake). Not all of these characteristics have been fully exploited by the pharmaceutical industry. This paper reports on work directed to better understanding how the characteristics of lactose particles affect their functional qualities.]]",

keywords = "lactose, drugs, saccharides, morphology",

author = "Listiohadi, {Yuanita D.} and Jim Hourigan and Steele, {Robert J.} and Johnson, {R. L.} and Sleigh, {Robert W.}",

year = "2002",

language = "English",

isbn = "0858257947",

booktitle = "World Congress on Particle Technology 4: Proceedings of the Symposium held in Sydney, N.S.W., 21-25 July, 2002",

publisher = "The Technical Committee",

note = "World Congress on Particle Technology ; Conference date: 01-01-2002",

}

TY - GEN

T1 - Lactose : polymorphism, caking behaviour and use in pharmaceuticals

AU - Listiohadi, Yuanita D.

AU - Hourigan, Jim

AU - Steele, Robert J.

AU - Johnson, R. L.

AU - Sleigh, Robert W.

PY - 2002

Y1 - 2002

N2 - ![CDATA[Lactose is an important ingredient used by the pharmaceutical industry, which is one of the largest consumers of the highly purified grades of this saccharide. Although the usual commercial product is crystalline a-lactose monohydrate, many users are unaware that lactose exists in numerous polymorphic and isomeric forms, each form possessing a range of unique particle characteristics such as flowability, compactibility, hygroscopicity, solubility, and shelf life (e.g. tendency to cake). Not all of these characteristics have been fully exploited by the pharmaceutical industry. This paper reports on work directed to better understanding how the characteristics of lactose particles affect their functional qualities.]]

AB - ![CDATA[Lactose is an important ingredient used by the pharmaceutical industry, which is one of the largest consumers of the highly purified grades of this saccharide. Although the usual commercial product is crystalline a-lactose monohydrate, many users are unaware that lactose exists in numerous polymorphic and isomeric forms, each form possessing a range of unique particle characteristics such as flowability, compactibility, hygroscopicity, solubility, and shelf life (e.g. tendency to cake). Not all of these characteristics have been fully exploited by the pharmaceutical industry. This paper reports on work directed to better understanding how the characteristics of lactose particles affect their functional qualities.]]

KW - lactose

KW - drugs

KW - saccharides

KW - morphology

UR - http://handle.uws.edu.au:8081/1959.7/37594

M3 - Conference Paper

SN - 0858257947

BT - World Congress on Particle Technology 4: Proceedings of the Symposium held in Sydney, N.S.W., 21-25 July, 2002

PB - The Technical Committee

T2 - World Congress on Particle Technology

Y2 - 1 January 2002

ER -

Lactose : polymorphism, caking behaviour and use in pharmaceuticals

Abstract

Conference

Keywords

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