Leopolic acid A, isolated from a terrestrial actinomycete, Streptomyces sp.

Ritesh Raju, Oleksandr Gromyko, Viktor Fedorenko, Andriy Luzhetskyy, Rolf Müller

    Research output: Contribution to journalArticlepeer-review

    20 Citations (Scopus)

    Abstract

    Chemical analysis of a terrestrial-derived Streptomyces sp. isolated from the rhizosphere of the plant Juniperus excels collected from the Crimean Mountains (Ukraine) yielded a new acid, leopolic acid A (1). Leopolic acid A (1) was identified to possess a rare ureido dipeptide, Phe-CO-Val, attached to a 5-dihydro-3-hydroxy-pyrrole-2-one ring. A detailed spectroscopic and Marfey's analysis led to the structure elucidation of leopolic acid A (1).
    Original languageEnglish
    Pages (from-to)6300-6301
    Number of pages2
    JournalTetrahedron Letters
    Volume53
    Issue number46
    Publication statusPublished - 2012

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