Long-term corneal biocompatibility of PFPE for an implantable contact lens

M. D.M. Evans; R. Z. Xie; B. Bojarski; T. C. Hughes; K. M. McLean; J. S. Wilkie; G. Y. Chan; G. Johnson; G. A. McFarland; A. Vannas; D. F. Sweeney

Long-term corneal biocompatibility of PFPE for an implantable contact lens

M. D.M. Evans, R. Z. Xie, B. Bojarski, T. C. Hughes, K. M. McLean, J. S. Wilkie, G. Y. Chan, G. Johnson, G. A. McFarland, A. Vannas, D. F. Sweeney

Research output: Chapter in Book / Conference Paper › Conference Paper

Abstract

Long-term corneal biocompatibility of perfluoropolyether (PFPE) for an implantable contact lens was discussed. Testing of corneal tissue to PFPE was performed by implanting lenticules under a LASIK-style flap in the rabbit cornea for up to 24 months. The corneas of animals were fixed for histological examination using routine light and electron microscopy (TEM) to assess the response of the corneal tissue to the surgery and the presence of the implanted lenticule. The PFPE lenticules showed good biocompatibility and optical clarity following implantation in the rabbit cornea over a 2-year test period. The operated eyes showed morphological features similar to those found in humans who have undergone laser refractive surgery.

Original language	English
Title of host publication	Transactions - 7th World Biomaterials Congress, 17 -21 May 2004, Sydney, Australia
Pages	116
Number of pages	1
Publication status	Published - 2004
Externally published	Yes
Event	World Biomaterials Congress - Sydney, Australia Duration: 17 May 2004 → 21 May 2004 Conference number: 7th

Conference

Conference	World Biomaterials Congress
Country/Territory	Australia
City	Sydney
Period	17/05/04 → 21/05/04

Cite this

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title = "Long-term corneal biocompatibility of PFPE for an implantable contact lens",

abstract = "Long-term corneal biocompatibility of perfluoropolyether (PFPE) for an implantable contact lens was discussed. Testing of corneal tissue to PFPE was performed by implanting lenticules under a LASIK-style flap in the rabbit cornea for up to 24 months. The corneas of animals were fixed for histological examination using routine light and electron microscopy (TEM) to assess the response of the corneal tissue to the surgery and the presence of the implanted lenticule. The PFPE lenticules showed good biocompatibility and optical clarity following implantation in the rabbit cornea over a 2-year test period. The operated eyes showed morphological features similar to those found in humans who have undergone laser refractive surgery.",

author = "Evans, {M. D.M.} and Xie, {R. Z.} and B. Bojarski and Hughes, {T. C.} and McLean, {K. M.} and Wilkie, {J. S.} and Chan, {G. Y.} and G. Johnson and McFarland, {G. A.} and A. Vannas and Sweeney, {D. F.}",

year = "2004",

language = "English",

isbn = "9781877040191",

pages = "116",

booktitle = "Transactions - 7th World Biomaterials Congress, 17 -21 May 2004, Sydney, Australia",

note = "World Biomaterials Congress ; Conference date: 17-05-2004 Through 21-05-2004",

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TY - GEN

T1 - Long-term corneal biocompatibility of PFPE for an implantable contact lens

AU - Evans, M. D.M.

AU - Xie, R. Z.

AU - Bojarski, B.

AU - Hughes, T. C.

AU - McLean, K. M.

AU - Wilkie, J. S.

AU - Chan, G. Y.

AU - Johnson, G.

AU - McFarland, G. A.

AU - Vannas, A.

AU - Sweeney, D. F.

N1 - Conference code: 7th

PY - 2004

Y1 - 2004

N2 - Long-term corneal biocompatibility of perfluoropolyether (PFPE) for an implantable contact lens was discussed. Testing of corneal tissue to PFPE was performed by implanting lenticules under a LASIK-style flap in the rabbit cornea for up to 24 months. The corneas of animals were fixed for histological examination using routine light and electron microscopy (TEM) to assess the response of the corneal tissue to the surgery and the presence of the implanted lenticule. The PFPE lenticules showed good biocompatibility and optical clarity following implantation in the rabbit cornea over a 2-year test period. The operated eyes showed morphological features similar to those found in humans who have undergone laser refractive surgery.

AB - Long-term corneal biocompatibility of perfluoropolyether (PFPE) for an implantable contact lens was discussed. Testing of corneal tissue to PFPE was performed by implanting lenticules under a LASIK-style flap in the rabbit cornea for up to 24 months. The corneas of animals were fixed for histological examination using routine light and electron microscopy (TEM) to assess the response of the corneal tissue to the surgery and the presence of the implanted lenticule. The PFPE lenticules showed good biocompatibility and optical clarity following implantation in the rabbit cornea over a 2-year test period. The operated eyes showed morphological features similar to those found in humans who have undergone laser refractive surgery.

UR - http://www.scopus.com/inward/record.url?scp=13844273236&partnerID=8YFLogxK

M3 - Conference Paper

AN - SCOPUS:13844273236

SN - 9781877040191

SP - 116

BT - Transactions - 7th World Biomaterials Congress, 17 -21 May 2004, Sydney, Australia

T2 - World Biomaterials Congress

Y2 - 17 May 2004 through 21 May 2004

ER -

Long-term corneal biocompatibility of PFPE for an implantable contact lens

Abstract

Conference

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