Measures of depression in Alzheimer’s disease

Ahmed A. Moustafa, Wafa Jaroudi, Ahmed Helal, Lily Bilson, Mohamad El Haj

Research output: Chapter in Book / Conference PaperChapter

1 Citation (Scopus)

Abstract

![CDATA[Depression impacts a large number of patients with dementia and Alzheimer’s disease (AD), with several studies reporting between 20% and 60% of AD patients diagnosed with depression (Reichman & Coyne, 1995). Diagnosing depressive disorder in dementia is difficult due to overlap in symptoms, poor communication of symptoms, and lack of insight (Burke, Goldfarb, Bollam, & Khokher, 2019; Dias, Barbosa, Kuang, & Teixeira, 2020). Shared symptoms between depression and dementia include sleep disturbances, changes in eating behavior, decreased initiative and interest (apathy), psychomotor agitation, poor concentration, anxiety, and tearfulness. Depressive symptoms not commonly seen in dementia without depression are consistent sadness, marked morning mood worsening, feelings of worthlessness or excessive or inappropriate guilt, recurrent thoughts of death and suicidal ideation or behaviors.]]
Original languageEnglish
Title of host publicationAlzheimer’s Disease: Understanding Biomarkers, Big Data, and Therapy
EditorsAhmed A. Moustafa
Place of PublicationU.K.
PublisherAcademic Press
Pages3-34
Number of pages32
ISBN (Print)9780128213346
DOIs
Publication statusPublished - 2022

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