TY - JOUR
T1 - Medicolegal Implications of Biphasic Anaphylaxis
AU - [Unknown], Ugo
AU - Moreschi, Carlo
AU - Marega, Giulia
AU - Tse, Rexson
AU - Garland, Jack
AU - Ondruschka, Benjamin
AU - Palmiere, Cristian
PY - 2021
Y1 - 2021
N2 - Biphasic anaphylaxis is an uncommon IgE-mediated condition whose pathophysiological mechanisms, risk factors, and predictive signs are not properly understood. Fortunately, the lethality of biphasic anaphylaxis, although probably underestimated, is low. Preventive clinical measures for biphasic anaphylaxis are neither standardized nor commonly applied. Furthermore, there are no laboratory protocols or anaphylactic markers to help identify the onset of biphasic anaphylaxis in clinical settings. The aim of this review is to highlight the medicolegal difficulties facing coroners and forensic pathologists in terms of the diagnosis and assessment of harm for victims and survivors of biphasic anaphylaxis.
AB - Biphasic anaphylaxis is an uncommon IgE-mediated condition whose pathophysiological mechanisms, risk factors, and predictive signs are not properly understood. Fortunately, the lethality of biphasic anaphylaxis, although probably underestimated, is low. Preventive clinical measures for biphasic anaphylaxis are neither standardized nor commonly applied. Furthermore, there are no laboratory protocols or anaphylactic markers to help identify the onset of biphasic anaphylaxis in clinical settings. The aim of this review is to highlight the medicolegal difficulties facing coroners and forensic pathologists in terms of the diagnosis and assessment of harm for victims and survivors of biphasic anaphylaxis.
UR - https://hdl.handle.net/1959.7/uws:65818
U2 - 10.1097/PAF.0000000000000621
DO - 10.1097/PAF.0000000000000621
M3 - Article
SN - 0195-7910
VL - 42
SP - 109
EP - 117
JO - American Journal of Forensic Medicine and Pathology
JF - American Journal of Forensic Medicine and Pathology
IS - 2
ER -