Mind-body therapies for cancer patients living with depression, anxiety or insomnia (MIRACLE) : a systematic review with individual participant data network meta-analysis

Yoann Birling; Sarah Nevitt; Deep Jyoti Bhuyan; Mingxian Jia; Fan Feng; Linda Ellen Carlson; Tiffany Pham; Jing Liu; Zahra Ayati; Liyi Nyiam; Zhichao Yu; Paul Fahey

doi:10.3390/mps4040076

Mind-body therapies for cancer patients living with depression, anxiety or insomnia (MIRACLE) : a systematic review with individual participant data network meta-analysis

Yoann Birling
, Sarah Nevitt
, Deep Jyoti Bhuyan
, Mingxian Jia
, Fan Feng
, Linda Ellen Carlson
, Tiffany Pham
, Jing Liu
, Zahra Ayati
, Liyi Nyiam
, Zhichao Yu
, Paul Fahey

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Depression, anxiety, and insomnia are common in cancer patients. Mind-body therapies (MBTs) are promising forms of treatment for cancer patients living with depression, anxiety, and insomnia. The objective of this study is to assess the effectiveness and acceptability of MBTs in cancer patients living with depression, anxiety, or insomnia. EMBase, PubMed, Cinahl, PsychINFO, IndMED, CSI-NISCAIR, CNKI, Clinicaltrial.gov, ChiCTR, and CTRI will be searched until October 2020 for relevant studies. Randomized controlled studies in which MBTs were tested in a cancer population will be selected. The authors of the selected studies will be contacted to obtain individual participant data. The participants who reached a defined clinical threshold for depression, anxiety, or insomnia will be selected for the three sub-studies on depression, anxiety, and insomnia, respectively. Pairwise and network meta-analyses will be used to assess the changes in depression, anxiety, sleep quality, and completion rate. We will assess the effect of the treatment dose (number and frequency of interventions) on effectiveness. The results of this study will inform clinical decision-making for the treatment of psychological disturbances in cancer patients. If MBTs are found effective, they will potentially be recommended as treatments for cancer patients with psychological symptoms.

Original language	English
Article number	76
Number of pages	10
Journal	Methods and Protocols
Volume	4
Issue number	4
DOIs	https://doi.org/10.3390/mps4040076
Publication status	Published - Dec 2021

Bibliographical note

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Open Access - Access Right Statement

Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.3390/mps4040076

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Birling, Y., Nevitt, S., Bhuyan, D. J., Jia, M., Feng, F., Carlson, L. E., Pham, T., Liu, J., Ayati, Z., Nyiam, L., Yu, Z., & Fahey, P. (2021). Mind-body therapies for cancer patients living with depression, anxiety or insomnia (MIRACLE) : a systematic review with individual participant data network meta-analysis. Methods and Protocols, 4(4), Article 76. https://doi.org/10.3390/mps4040076

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title = "Mind-body therapies for cancer patients living with depression, anxiety or insomnia (MIRACLE) : a systematic review with individual participant data network meta-analysis",

abstract = "Depression, anxiety, and insomnia are common in cancer patients. Mind-body therapies (MBTs) are promising forms of treatment for cancer patients living with depression, anxiety, and insomnia. The objective of this study is to assess the effectiveness and acceptability of MBTs in cancer patients living with depression, anxiety, or insomnia. EMBase, PubMed, Cinahl, PsychINFO, IndMED, CSI-NISCAIR, CNKI, Clinicaltrial.gov, ChiCTR, and CTRI will be searched until October 2020 for relevant studies. Randomized controlled studies in which MBTs were tested in a cancer population will be selected. The authors of the selected studies will be contacted to obtain individual participant data. The participants who reached a defined clinical threshold for depression, anxiety, or insomnia will be selected for the three sub-studies on depression, anxiety, and insomnia, respectively. Pairwise and network meta-analyses will be used to assess the changes in depression, anxiety, sleep quality, and completion rate. We will assess the effect of the treatment dose (number and frequency of interventions) on effectiveness. The results of this study will inform clinical decision-making for the treatment of psychological disturbances in cancer patients. If MBTs are found effective, they will potentially be recommended as treatments for cancer patients with psychological symptoms.",

author = "Yoann Birling and Sarah Nevitt and Bhuyan, \{Deep Jyoti\} and Mingxian Jia and Fan Feng and Carlson, \{Linda Ellen\} and Tiffany Pham and Jing Liu and Zahra Ayati and Liyi Nyiam and Zhichao Yu and Paul Fahey",

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language = "English",

volume = "4",

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Birling, Y, Nevitt, S, Bhuyan, DJ, Jia, M, Feng, F, Carlson, LE, Pham, T, Liu, J, Ayati, Z, Nyiam, L, Yu, Z & Fahey, P 2021, 'Mind-body therapies for cancer patients living with depression, anxiety or insomnia (MIRACLE) : a systematic review with individual participant data network meta-analysis', Methods and Protocols, vol. 4, no. 4, 76. https://doi.org/10.3390/mps4040076

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AU - Birling, Yoann

AU - Nevitt, Sarah

AU - Bhuyan, Deep Jyoti

AU - Jia, Mingxian

AU - Feng, Fan

AU - Carlson, Linda Ellen

AU - Pham, Tiffany

AU - Liu, Jing

AU - Ayati, Zahra

AU - Nyiam, Liyi

AU - Yu, Zhichao

AU - Fahey, Paul

PY - 2021/12

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AB - Depression, anxiety, and insomnia are common in cancer patients. Mind-body therapies (MBTs) are promising forms of treatment for cancer patients living with depression, anxiety, and insomnia. The objective of this study is to assess the effectiveness and acceptability of MBTs in cancer patients living with depression, anxiety, or insomnia. EMBase, PubMed, Cinahl, PsychINFO, IndMED, CSI-NISCAIR, CNKI, Clinicaltrial.gov, ChiCTR, and CTRI will be searched until October 2020 for relevant studies. Randomized controlled studies in which MBTs were tested in a cancer population will be selected. The authors of the selected studies will be contacted to obtain individual participant data. The participants who reached a defined clinical threshold for depression, anxiety, or insomnia will be selected for the three sub-studies on depression, anxiety, and insomnia, respectively. Pairwise and network meta-analyses will be used to assess the changes in depression, anxiety, sleep quality, and completion rate. We will assess the effect of the treatment dose (number and frequency of interventions) on effectiveness. The results of this study will inform clinical decision-making for the treatment of psychological disturbances in cancer patients. If MBTs are found effective, they will potentially be recommended as treatments for cancer patients with psychological symptoms.

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ER -

Mind-body therapies for cancer patients living with depression, anxiety or insomnia (MIRACLE) : a systematic review with individual participant data network meta-analysis

Abstract

Bibliographical note

Open Access - Access Right Statement

UN SDGs

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