Modelling of diffusion in cultured epithelial cell spheroids

Sisi Liang, Madiha Yunus, Eleftheria Panagiotaki, Byung Kim, Timothy Stait-Gardner, Mikhail Zubkov, Brian Hawkett, William Price, Carl Power, Roger Bourne

Research output: Chapter in Book / Conference PaperConference Paperpeer-review

Abstract

![CDATA[Cultured epithelial cell spheroids demonstrate many of the physiological properties of glandular epithelia and provide an ideal experimental model for investigation of the distinctive structural properties that may contribute to the reported low water mobility in prostate, breast, and gut epithelia. The structural connections are very similar to those in intact tissue and thus they provide a more realistic model of tissue than previously investigated models based on pelleted yeast or erythrocyte cells. We report an investigation of the correlation between known cell sizes in a spheroid culture and restriction radius estimated by a model of diffusion MRI signals.]]
Original languageEnglish
Title of host publication24th Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine, 07-13 May 2016, Singapore
PublisherInternational Society for Magnetic Resonance in Medicine
Number of pages2
Publication statusPublished - 2016
EventInternational Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition -
Duration: 1 Jan 2016 → …

Conference

ConferenceInternational Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition
Period1/01/16 → …

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