Musk and ambergris aphrodisiacs in the premodern intercultural origins of endocrine pharmacy

This article explores the historical uses of two animal medicines that are understood in current biomedicine to have potential endocrine activity: deer musk and whale ambergris, which were prized as aphrodisiacs in the early-modern world. It diverges from the focus in existing scholarship on nineteenth-century gonadal organotherapy as the precursor for the modern discovery of the sex-steroid hormones, looking instead at the older examples of deer musk and whale ambergris that were commonly prescribed both in medieval Islamicate and early-modern European Christianate medical sources. The early-modern Latin, French, German and English description of these substances as fertility, aphrodisiac, and rejuvenative remedies indicates a direct exchange of pharmacological concepts and substances relating to the human sexual and reproductive systems between Europe and the Middle East from the sixteenth to eighteenth centuries. The article explores how musk and ambergris were used in early-modern Western medicine, and how knowledge of them circulated across cultures. I argue that musk and ambergris, which were both thought to have effects on vitality, fertility, and potency in medieval Middle Eastern and early-modern European traditions, trouble the view of the origins of sex-steroid hormone endocrinology as deriving purely from modern European gonadal opotherapy. The valuing of these substances as fertility, vitality, and aphrodisiac remedies in the work of early-modern European physicians was indicative of both the globalization of medical knowledge, and an increased commercial trade in pharmacological material goods, confirming the view of medical globalization as a multi-directional historical process constituted in both conceptual and material terms.