Neurovascular coupling and distribution of cerebral blood flow during exercise

C. K. Willie; E. C. Cowan; P. N. Ainslie; C. E. Taylor; K. J. Smith; P. Y. W. Sin; Y. C. Tzeng

doi:10.1016/j.jneumeth.2011.03.017

Neurovascular coupling and distribution of cerebral blood flow during exercise

C. K. Willie, E. C. Cowan, P. N. Ainslie, C. E. Taylor, K. J. Smith, P. Y. W. Sin, Y. C. Tzeng

School of Health Sciences

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

We examined how cerebral blood flow velocity (CBV) and neurovascular coupling is influenced by exercise. Blood velocities in the posterior and middle cerebral arteries (PCAv and MCAv) during rest and cycling exercise at 60% estimated maximal oxygen consumption were measured. Neurovascular coupling was quantified as the Î”PCAv with visual stimulation. During exercise, despite a 15.2. ÃƒÂ‚Ã‚Â± 13.6% and 26.1. ÃƒÂ‚Ã‚Â± 22.5% increase from rest in the MCAv and PCAv, respectively, neurovascular coupling was unaltered. Thus, despite regionally heterogeneous elevations in CBV during exercise, neurometabolic coupling is maintained.

Original language	English
Pages (from-to)	270-273
Number of pages	4
Journal	Journal of Neuroscience Methods
Volume	198
Issue number	2
DOIs	https://doi.org/10.1016/j.jneumeth.2011.03.017
Publication status	Published - 2011

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10.1016/j.jneumeth.2011.03.017

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title = "Neurovascular coupling and distribution of cerebral blood flow during exercise",

abstract = "We examined how cerebral blood flow velocity (CBV) and neurovascular coupling is influenced by exercise. Blood velocities in the posterior and middle cerebral arteries (PCAv and MCAv) during rest and cycling exercise at 60% estimated maximal oxygen consumption were measured. Neurovascular coupling was quantified as the {\^I}”PCAv with visual stimulation. During exercise, despite a 15.2. {\~A}ƒ{\^A}‚{\~A}‚{\^A}± 13.6% and 26.1. {\~A}ƒ{\^A}‚{\~A}‚{\^A}± 22.5% increase from rest in the MCAv and PCAv, respectively, neurovascular coupling was unaltered. Thus, despite regionally heterogeneous elevations in CBV during exercise, neurometabolic coupling is maintained.",

author = "Willie, {C. K.} and Cowan, {E. C.} and Ainslie, {P. N.} and Taylor, {C. E.} and Smith, {K. J.} and Sin, {P. Y. W.} and Tzeng, {Y. C.}",

year = "2011",

doi = "10.1016/j.jneumeth.2011.03.017",

language = "English",

volume = "198",

pages = "270--273",

journal = "Journal of Neuroscience Methods",

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TY - JOUR

T1 - Neurovascular coupling and distribution of cerebral blood flow during exercise

AU - Willie, C. K.

AU - Cowan, E. C.

AU - Ainslie, P. N.

AU - Taylor, C. E.

AU - Smith, K. J.

AU - Sin, P. Y. W.

AU - Tzeng, Y. C.

PY - 2011

Y1 - 2011

N2 - We examined how cerebral blood flow velocity (CBV) and neurovascular coupling is influenced by exercise. Blood velocities in the posterior and middle cerebral arteries (PCAv and MCAv) during rest and cycling exercise at 60% estimated maximal oxygen consumption were measured. Neurovascular coupling was quantified as the Î”PCAv with visual stimulation. During exercise, despite a 15.2. ÃƒÂ‚Ã‚Â± 13.6% and 26.1. ÃƒÂ‚Ã‚Â± 22.5% increase from rest in the MCAv and PCAv, respectively, neurovascular coupling was unaltered. Thus, despite regionally heterogeneous elevations in CBV during exercise, neurometabolic coupling is maintained.

AB - We examined how cerebral blood flow velocity (CBV) and neurovascular coupling is influenced by exercise. Blood velocities in the posterior and middle cerebral arteries (PCAv and MCAv) during rest and cycling exercise at 60% estimated maximal oxygen consumption were measured. Neurovascular coupling was quantified as the Î”PCAv with visual stimulation. During exercise, despite a 15.2. ÃƒÂ‚Ã‚Â± 13.6% and 26.1. ÃƒÂ‚Ã‚Â± 22.5% increase from rest in the MCAv and PCAv, respectively, neurovascular coupling was unaltered. Thus, despite regionally heterogeneous elevations in CBV during exercise, neurometabolic coupling is maintained.

UR - http://handle.uws.edu.au:8081/1959.7/553761

U2 - 10.1016/j.jneumeth.2011.03.017

DO - 10.1016/j.jneumeth.2011.03.017

M3 - Article

C2 - 21459113

SN - 0165-0270

VL - 198

SP - 270

EP - 273

JO - Journal of Neuroscience Methods

JF - Journal of Neuroscience Methods

IS - 2

ER -

Neurovascular coupling and distribution of cerebral blood flow during exercise

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