Novel parameters for rapid blood separation on a centrifugal platform

T. H. Kim, R. Gorkin, M. Madou, Y. K. Cho

Research output: Chapter in Book / Conference PaperConference Paperpeer-review

1 Citation (Scopus)

Abstract

Blood separation is often the first step in medical diagnostics. In this article, we demonstrate faster separation of plasma from human whole blood in slanted channel on a centrifugal microfluidic platform. Polycarbonate was used for fabrication of disc and customized visualization system was used to evaluate the performance of each microfluidic channel. Experimental results showed that sedimentation speed at 60° inclined channel with respect to the radial direction was about 50% faster than the result achieved in 0° inclined (radial direction) channel. Furthermore, the effect of the inclined channel was more enhanced when higher hematocrit sample was used. While the Boycott effect can be applied to explain this phenomenon, we are under investigation of more detailed parameters that can be unique in centrifugal microfluidic devices.

Original languageEnglish
Title of host publicationNanotechnology 2010
Subtitle of host publicationElectronics, Devices, Fabrication, MEMS, Fluidics and Computational - Technical Proceedings of the 2010 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2010
Pages456-459
Number of pages4
Publication statusPublished - 2010
Externally publishedYes
EventNanotechnology 2010: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2010 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2010 - Anaheim, CA, United States
Duration: 21 Jun 201024 Jun 2010

Publication series

NameNanotechnology 2010: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - Technical Proceedings of the 2010 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2010
Volume2

Conference

ConferenceNanotechnology 2010: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2010 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2010
Country/TerritoryUnited States
CityAnaheim, CA
Period21/06/1024/06/10

Keywords

  • Blood separation
  • Boycott effect
  • Centrifugal microfluidic device
  • Inclined channel
  • Plasma

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