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Oral microbiome and treatment resistance status in schizophrenia: a cross-sectional study

  • Anoop Sankaranarayanan
  • , Preethi Ramanathan
  • , Martha Zakrzewski
  • , Deepali Vasani
  • , Ramanathan Ganapathy
  • , Vlasios Brakoulias
  • , Mark W. Douglas
  • Western Sydney Local Health District
  • Australian Genome Research Facility Ltd.
  • The University of Sydney

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
4 Downloads (Pure)

Abstract

Early identification may lead to improved outcomes in treatment- resistant schizophrenia (TRS), a condition otherwise associated with worse clinical and functional outcomes.2 Microbiomes, both gut and oral, influence brain functioning via the hypothalamic–pituitary–adrenal (HPA) axis, vagus nerve, tryptophan metabolism, and immune modulation, which makes them a biomarker candidate for TRS.
Original languageEnglish
Pages (from-to)97-99
Number of pages3
JournalIndian Journal of Psychological Medicine
Volume47
Issue number1
DOIs
Publication statusPublished - Jan 2025

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