Pharmacognosy of Centipeda cunninghamii, an endemic Australian traditional medicinal plant

D. N. Leach, R. N. Spooner-Hart, K. D. Beattie

Research output: Chapter in Book / Conference PaperConference Paperpeer-review

1 Citation (Scopus)

Abstract

![CDATA[Centipeda is a genus in the family Asteraceae comprising 12 taxa in 10 species. All but one species occur in Australia. There are documented traditional medicinal uses of five species across Australia, India and China. Investigations of the aqueous ethanolic extract of C. cunninghamii (DC) A. Braun & Asch, have confirmed its antiinflammatory and antioxidant (ORAC) activity. Detailed investigations suggest that the extract acts against a range of inflammatory markers including; PGE2 COX, NO and TNF-α, but not through the lipoxygenase pathway. Seventeen compounds were isolated and subsequent bioassays indicated that the anti-inflammatory activity was linked to flavonoids and terpenoids, whilst the antioxidant activity was attributed to both flavonoids and a group of novel heptenedioic acid caffeoyl esters. Quality control for medicinal plant production of this species has utilised the levels of phenolics, flavonoids and sequiterpenes to optimise growing and extraction parameters.]]
Original languageEnglish
Title of host publicationProceedings of the V World Congress on Medicinal and Aromatic Plants and International Symposium on Plants, as Factories of Natural Substances, Edible and Essential Oils: Brisbane, Australia, August 17-22, 2014
PublisherInternational Society for Horticultural Science
Pages47-56
Number of pages10
ISBN (Print)9789462611313
DOIs
Publication statusPublished - 2016
EventInternational Horticultural Congress -
Duration: 17 Aug 2014 → …

Publication series

Name
ISSN (Print)0567-7572

Conference

ConferenceInternational Horticultural Congress
Period17/08/14 → …

Keywords

  • Centipeda cunninghamii
  • anti-inflammatory agents
  • antioxidants
  • herbs
  • therapeutic use

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