TY - JOUR
T1 - Pimprinols A-C, from the terrestrial actinomycete, Streptomyces sp.
AU - Raju, Ritesh
AU - Gromyko, Oleksandr
AU - Fedorenko, Viktor
AU - Luzhetskyy, Andriy
AU - Müller, Rolf
PY - 2012
Y1 - 2012
N2 - A Streptomyces sp. Lv3-13, isolated from the rhizosphere soil of the plant Mespilus germanica, has yielded three new pimprinine derivatives, named pimprinols A-C (1-3) and the unknown (2-aminophenyl)(2-ethyloxazol-5-yl) methanone (4) along with the known compounds 2-ethyl oxazole pimprinine and 2-propyl oxazole pimprinine. The structures of the compounds were elucidated based on spectroscopic methods including UV, HR-ESIMS and 1D, 2D NMR data. Compounds 1-4 were screened for antimicrobial and cytotoxic activities.
AB - A Streptomyces sp. Lv3-13, isolated from the rhizosphere soil of the plant Mespilus germanica, has yielded three new pimprinine derivatives, named pimprinols A-C (1-3) and the unknown (2-aminophenyl)(2-ethyloxazol-5-yl) methanone (4) along with the known compounds 2-ethyl oxazole pimprinine and 2-propyl oxazole pimprinine. The structures of the compounds were elucidated based on spectroscopic methods including UV, HR-ESIMS and 1D, 2D NMR data. Compounds 1-4 were screened for antimicrobial and cytotoxic activities.
UR - http://handle.uws.edu.au:8081/1959.7/544868
UR - http://www.sciencedirect.com/science/article/pii/S0040403912005618
M3 - Article
SN - 0040-4039
VL - 53
SP - 3009
EP - 3011
JO - Tetrahedron Letters
JF - Tetrahedron Letters
IS - 24
ER -