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Plants derived therapeutic strategies targeting chronic respiratory diseases: Chemical and immunological perspective

  • Parteek Prasher
  • , Mousmee Sharma
  • , Meenu Mehta
  • , Keshav R. Paudel
  • , Saurabh Satija
  • , Dinesh K. Chellappan
  • , Harish Dureja
  • , Gaurav Gupta
  • , Murtaza M. Tambuwala
  • , Poonam Negi
  • , Peter R. Wich
  • , Nicole G. Hansbro
  • , Philip M. Hansbro
  • , Kamal Dua
  • University of Petroleum and Energy Studies
  • Uttaranchal University
  • University of Technology Sydney
  • Centenary Institute
  • Centre for Inflammation
  • School of Life Sciences
  • Lovely Professional University
  • International Medical University
  • Maharshi Dayanand University
  • Suresh Gyan Vihar University
  • Ulster University
  • Shoolini University of Biotechnology and Management Sciences
  • University of New South Wales
  • University of Newcastle
  • Discipline of Pharmacy
  • School of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

Abstract

The apparent predicament of the representative chemotherapy for managing respiratory distress calls for an obligatory deliberation for identifying the pharmaceuticals that effectively counter the contemporary intricacies associated with target disease. Multiple, complex regulatory pathways manifest chronic pulmonary disorders, which require chemotherapeutics that produce composite inhibitory effect. The cost effective natural product based molecules hold a high fervor to meet the prospects posed by current respiratory-distress therapy by sparing the tedious drug design and development archetypes, present a robust standing for the possible replacement of the fading practice of poly-pharmacology, and ensure the subversion of a potential disease relapse. This study summarizes the experimental evidences on natural products moieties and their components that illustrates therapeutic efficacy on respiratory disorders.

Original languageEnglish
Article number109125
JournalChemico-Biological Interactions
Volume325
DOIs
Publication statusPublished - Jul 2020
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2020 Elsevier B.V.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Alkaloids
  • COPD
  • Flavonoids
  • Natural products
  • Respiratory disorders

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