Platinum(II) intercalating complexes based on 2,2':6',2"-terpyridine

Benjamin W. J. Harper; Marcelis van Holst; Janice Aldrich-Wright

doi:10.1007/978-3-211-99079-7_4

Platinum(II) intercalating complexes based on 2,2':6',2"-terpyridine

Benjamin W. J. Harper, Marcelis van Holst, Janice Aldrich-Wright

Research output: Chapter in Book / Conference Paper › Chapter

Abstract

New complexes with similar structures to cispatin very rarely offer any significant benefits to those analogues already in clinical use. This has caused considerable interest in other platinum complexes, particularly mettallointercalators as it is believed these complexes could display a different spectrum of anticancer activity due to their different mode of binding.

Original language	English
Title of host publication	Metallointercalators: Synthesis and Techniques to Probe Their Interactions with Biomolecules
Editors	Janice R. Aldrich-Wright
Place of Publication	U.S.
Publisher	Springer
Pages	101-128
Number of pages	28
ISBN (Electronic)	9783211990797
ISBN (Print)	9783211094273
DOIs	https://doi.org/10.1007/978-3-211-99079-7_4
Publication status	Published - 2011

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10.1007/978-3-211-99079-7_4

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abstract = "New complexes with similar structures to cispatin very rarely offer any significant benefits to those analogues already in clinical use. This has caused considerable interest in other platinum complexes, particularly mettallointercalators as it is believed these complexes could display a different spectrum of anticancer activity due to their different mode of binding.",

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AB - New complexes with similar structures to cispatin very rarely offer any significant benefits to those analogues already in clinical use. This has caused considerable interest in other platinum complexes, particularly mettallointercalators as it is believed these complexes could display a different spectrum of anticancer activity due to their different mode of binding.

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Platinum(II) intercalating complexes based on 2,2':6',2"-terpyridine

Abstract

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