Primary lymphoma of the ampulla of vater

Joya Pawade; Soon C. Lee; David W. Ellis; Ivo D.A. Vellar; Jurgen Rode

doi:10.1002/1097-0142(19940415)73:8<2083::AID-CNCR2820730812>3.0.CO;2-B

Primary lymphoma of the ampulla of vater

Joya Pawade, Soon C. Lee, David W. Ellis, Ivo D.A. Vellar, Jurgen Rode

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

A 57‐year‐old woman was investigated for obstructive jaundice with endoscopic retrograde cholangiopancreaticography that showed a tumor at the ampulla of Vater. A Whipple's procedure was performed. A protuberant tumor was present at the ampulla of Vater in the background of multiple mucosal polyps in the duodenum. Light microscopy revealed a diffuse non‐Hodgkin's lymphoma with centrocytelike cells forming lymphoepithelial lesions and infiltrating the sphincter of Oddi. The duodenal polyps were hyperplastic lymphoid follicles with reactive germinal centers. Immunohistochemical staining characterized the tumor as a B‐cell neoplasm with IgA heavy‐chain and lambda light‐chain restrictions. Complete remission of the disease occurred after surgery. The clinical, histologic, and immunohistochemical features of this lymphoma are suggestive of histogenetic derivation from mucosal‐associated tissue.

Original language	English
Pages (from-to)	2083-2086
Number of pages	4
Journal	Cancers
Volume	73
Issue number	8
DOIs	https://doi.org/10.1002/1097-0142(19940415)73:8<2083::AID-CNCR2820730812>3.0.CO;2-B
Publication status	Published - 15 Apr 1994
Externally published	Yes

Keywords

Ampulla of Vater
duodenal lymphoid hyperplasia
extra‐nodal lymphoma
mucosa‐associated lymphoid tissue (MALT)

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10.1002/1097-0142(19940415)73:8<2083::AID-CNCR2820730812>3.0.CO;2-B

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title = "Primary lymphoma of the ampulla of vater",

abstract = "A 57‐year‐old woman was investigated for obstructive jaundice with endoscopic retrograde cholangiopancreaticography that showed a tumor at the ampulla of Vater. A Whipple's procedure was performed. A protuberant tumor was present at the ampulla of Vater in the background of multiple mucosal polyps in the duodenum. Light microscopy revealed a diffuse non‐Hodgkin's lymphoma with centrocytelike cells forming lymphoepithelial lesions and infiltrating the sphincter of Oddi. The duodenal polyps were hyperplastic lymphoid follicles with reactive germinal centers. Immunohistochemical staining characterized the tumor as a B‐cell neoplasm with IgA heavy‐chain and lambda light‐chain restrictions. Complete remission of the disease occurred after surgery. The clinical, histologic, and immunohistochemical features of this lymphoma are suggestive of histogenetic derivation from mucosal‐associated tissue.",

keywords = "Ampulla of Vater, duodenal lymphoid hyperplasia, extra‐nodal lymphoma, mucosa‐associated lymphoid tissue (MALT)",

author = "Joya Pawade and Lee, {Soon C.} and Ellis, {David W.} and Vellar, {Ivo D.A.} and Jurgen Rode",

year = "1994",

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T1 - Primary lymphoma of the ampulla of vater

AU - Pawade, Joya

AU - Lee, Soon C.

AU - Ellis, David W.

AU - Vellar, Ivo D.A.

AU - Rode, Jurgen

PY - 1994/4/15

Y1 - 1994/4/15

N2 - A 57‐year‐old woman was investigated for obstructive jaundice with endoscopic retrograde cholangiopancreaticography that showed a tumor at the ampulla of Vater. A Whipple's procedure was performed. A protuberant tumor was present at the ampulla of Vater in the background of multiple mucosal polyps in the duodenum. Light microscopy revealed a diffuse non‐Hodgkin's lymphoma with centrocytelike cells forming lymphoepithelial lesions and infiltrating the sphincter of Oddi. The duodenal polyps were hyperplastic lymphoid follicles with reactive germinal centers. Immunohistochemical staining characterized the tumor as a B‐cell neoplasm with IgA heavy‐chain and lambda light‐chain restrictions. Complete remission of the disease occurred after surgery. The clinical, histologic, and immunohistochemical features of this lymphoma are suggestive of histogenetic derivation from mucosal‐associated tissue.

AB - A 57‐year‐old woman was investigated for obstructive jaundice with endoscopic retrograde cholangiopancreaticography that showed a tumor at the ampulla of Vater. A Whipple's procedure was performed. A protuberant tumor was present at the ampulla of Vater in the background of multiple mucosal polyps in the duodenum. Light microscopy revealed a diffuse non‐Hodgkin's lymphoma with centrocytelike cells forming lymphoepithelial lesions and infiltrating the sphincter of Oddi. The duodenal polyps were hyperplastic lymphoid follicles with reactive germinal centers. Immunohistochemical staining characterized the tumor as a B‐cell neoplasm with IgA heavy‐chain and lambda light‐chain restrictions. Complete remission of the disease occurred after surgery. The clinical, histologic, and immunohistochemical features of this lymphoma are suggestive of histogenetic derivation from mucosal‐associated tissue.

KW - Ampulla of Vater

KW - duodenal lymphoid hyperplasia

KW - extra‐nodal lymphoma

KW - mucosa‐associated lymphoid tissue (MALT)

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VL - 73

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JO - Cancers

JF - Cancers

IS - 8

ER -

Primary lymphoma of the ampulla of vater

Abstract

Keywords

UN SDGs

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