Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry

Jennifer L. Beck; Rajesh Gupta; Nyree L. Williamson; Margaret M. Sheil; Janice R. Aldrich-Wright; Stephen F. Ralph

doi:10.1039/b212132h

Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry

Jennifer L. Beck
, Rajesh Gupta
, Nyree L. Williamson
, Margaret M. Sheil
, Janice R. Aldrich-Wright
, Stephen F. Ralph

School of Science

University of Wollongong

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

ESI mass spectra show that up to five ruthenium molecules can bind non-covalently to double stranded 16mer DNA, and provide information on the relative affinity and DNA sequence selectivity of different ruthenium complexes.

Original language	English
Pages (from-to)	626-627
Number of pages	2
Journal	Chemical Communications
Volume	3
Issue number	5
DOIs	https://doi.org/10.1039/b212132h
Publication status	Published - 2003

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title = "Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry",

abstract = "ESI mass spectra show that up to five ruthenium molecules can bind non-covalently to double stranded 16mer DNA, and provide information on the relative affinity and DNA sequence selectivity of different ruthenium complexes.",

author = "Beck, \{Jennifer L.\} and Rajesh Gupta and Williamson, \{Nyree L.\} and Sheil, \{Margaret M.\} and Aldrich-Wright, \{Janice R.\} and Ralph, \{Stephen F.\}",

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doi = "10.1039/b212132h",

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T1 - Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry

AU - Beck, Jennifer L.

AU - Gupta, Rajesh

AU - Williamson, Nyree L.

AU - Sheil, Margaret M.

AU - Aldrich-Wright, Janice R.

AU - Ralph, Stephen F.

PY - 2003

Y1 - 2003

N2 - ESI mass spectra show that up to five ruthenium molecules can bind non-covalently to double stranded 16mer DNA, and provide information on the relative affinity and DNA sequence selectivity of different ruthenium complexes.

AB - ESI mass spectra show that up to five ruthenium molecules can bind non-covalently to double stranded 16mer DNA, and provide information on the relative affinity and DNA sequence selectivity of different ruthenium complexes.

UR - https://www.scopus.com/pages/publications/0037423976

U2 - 10.1039/b212132h

DO - 10.1039/b212132h

M3 - Article

C2 - 12669857

AN - SCOPUS:0037423976

SN - 1359-7345

VL - 3

SP - 626

EP - 627

JO - Chemical Communications

JF - Chemical Communications

IS - 5

ER -

Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry

Abstract

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